Hara-Kudo Y, Miyahara M, Kumagai S
Department of Biomedical Food Research, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo 162-8640, USA.
Appl Environ Microbiol. 2000 Dec;66(12):5540-3. doi: 10.1128/AEM.66.12.5540-5543.2000.
Verotoxin (VT)-producing Escherichia coli O157:H7 was culturable on agar media after being left in water for 21 months. However, there were a number of colonies which had lost O157 O antigenicity. These colonies produced VTs, which are pathogenic to humans. These observations suggest that the immunologic methods based on O157 O antigenicity are unable to detect and isolate VT-producing E. coli in foods and other environments if the organism has been under starvation conditions for a long period.
产志贺毒素(VT)的大肠杆菌O157:H7在水中放置21个月后仍可在琼脂培养基上培养。然而,有许多菌落已丧失O157 O抗原性。这些菌落产生对人类致病的VT。这些观察结果表明,如果该生物体长期处于饥饿状态,基于O157 O抗原性的免疫学方法无法检测和分离食品及其他环境中产VT的大肠杆菌。