Becker D F, Grilo C M, Edell W S, McGlashan T H
Yale Psychiatric Institute, Yale University, New Haven, Connecticut, USA.
Am J Psychiatry. 2000 Dec;157(12):2011-6. doi: 10.1176/appi.ajp.157.12.2011.
The authors examined the comorbidity of borderline personality disorder with other personality disorders in a series of consecutively admitted adolescents. For comparison, the comorbidity of borderline personality disorder with other personality disorders was also examined in a series of adults consecutively admitted to the same hospital during the same period.
A total of 138 adolescents and 117 adults were reliably assessed with the Personality Disorder Examination, a semistructured diagnostic interview for DSM-III-R personality disorders. Sixty-eight adolescents and 50 adults met the diagnostic criteria for borderline personality disorder. The co-occurrence of other personality disorders in the group of subjects with borderline personality disorder was statistically compared to that in the group without borderline personality disorder, for adolescents and adults separately.
For the adults, Bonferroni-corrected chi-square analysis revealed significant diagnostic co-occurrence with borderline personality disorder for antisocial personality disorder only. For the adolescents, borderline personality disorder showed significant co-occurrence with schizotypal and passive-aggressive personality disorders.
In the adults, borderline personality disorder was significantly comorbid only with another cluster B disorder. The adolescents, by comparison, displayed a broader pattern of comorbidity of borderline personality disorder, encompassing aspects of clusters A and C. These results suggest that the borderline personality disorder diagnosis may represent a more diffuse range of psychopathology in adolescents than in adults.
作者研究了一系列连续入院青少年中边缘型人格障碍与其他人格障碍的共病情况。为作比较，还研究了同一时期在同一家医院连续入院的一系列成年人中边缘型人格障碍与其他人格障碍的共病情况。
使用人格障碍检查对总共138名青少年和117名成年人进行了可靠评估，人格障碍检查是一种针对DSM-III-R人格障碍的半结构化诊断访谈。68名青少年和50名成年人符合边缘型人格障碍的诊断标准。分别对青少年和成年人中边缘型人格障碍组与非边缘型人格障碍组中其他人格障碍的共病情况进行统计学比较。
对于成年人，经Bonferroni校正的卡方分析显示，仅反社会人格障碍与边缘型人格障碍存在显著的诊断共病。对于青少年，边缘型人格障碍与分裂型人格障碍和被动攻击型人格障碍存在显著共病。
在成年人中，边缘型人格障碍仅与另一组B类障碍存在显著共病。相比之下，青少年中边缘型人格障碍的共病模式更为广泛，包括A组和C组的一些方面。这些结果表明，边缘型人格障碍诊断在青少年中可能比在成年人中代表更广泛的精神病理学范围。
