Babbs C F
Indiana University School of Medicine, West Lafayette, USA.
Crit Care Med. 2000 Nov;28(11 Suppl):N199-202. doi: 10.1097/00003246-200011001-00007.
This study was undertaken to understand and predict results of experimental cardiopulmonary resuscitation (CPR) techniques involving compression and decompression of either the chest or the abdomen. Simple mathematical models of the adult human circulation were used. Assumptions of the models are limited to normal human anatomy and physiology, the definition of compliance (volume change/pressure change), and Ohm's law (flow = pressure/resistance). Interposed abdominal compression-CPR, active compression and decompression of the chest, and Lifestick CPR, which combines interposed abdominal compression and active compression and decompression, produce, respectively, 1.9-, 1.2-, and 2.4-fold greater blood flow than standard CPR and systemic perfusion pressures of 45, 30, and 58 mm Hg, respectively. These positive effects are explained by improved pump priming and are consequences of fundamental principles of cardiovascular physiology.
本研究旨在了解并预测涉及胸部或腹部按压与减压的实验性心肺复苏（CPR）技术的效果。使用了成人人体循环的简单数学模型。模型的假设仅限于正常人体解剖学和生理学、顺应性的定义（容积变化/压力变化）以及欧姆定律（流量 = 压力/阻力）。插入式腹部按压心肺复苏、胸部主动按压与减压以及结合了插入式腹部按压与胸部主动按压与减压的生命棒心肺复苏，分别比标准心肺复苏产生的血流量高1.9倍、1.2倍和2.4倍，全身灌注压分别为45 mmHg、30 mmHg和58 mmHg。这些积极效果可通过改善泵的灌注来解释，并且是心血管生理学基本原理的结果。
