Boone J M, Cooper V N, Nemzek W R, McGahan J P, Seibert J A
Department of Radiology, University of California, Davis, UC Davis Medical Center, Sacramento 95817, USA.
Med Phys. 2000 Oct;27(10):2393-407. doi: 10.1118/1.1312809.
The assessment of the radiation dose to internal organs or to an embryo or fetus is required on occasion for risk assessment or for comparing imaging studies. Limited resources hinder the ability to accurately assess the radiation dose received to locations outside the tissue volume actually scanned during computed tomography (CT). The purpose of this study was to assess peripheral doses and provide tabular data for dose evaluation. Validated Monte Carlo simulation techniques were used to compute the dose distribution along the length of water-equivalent cylindrical phantoms, 16 and 32 cm in diameter. For further validation, comparisons between physically measured and Monte Carlo-derived air kerma profiles were performed and showed excellent (1% to 2%) agreement. Polyenergetic x-ray spectra at 80, 100, 120, and 140 kVp with beam shaping filters were studied. Using 10(8) simulated photons input to the cylinders perpendicular to their long axis, line spread functions (LSF) of the dose distribution were determined at three depths in the cylinders (center, mid-depth, and surface). The LSF data were then used with appropriate mathematics to compute dose distributions along the long axis of the cylinder. The dose distributions resulting from helical (pitch = 1.0) scans and axial scans were approximately equivalent. Beyond about 3 cm from the edge of the CT scanned tissue volume, the fall-off of radiation dose was exponential. A series of tables normalized at 100 milliampere seconds (mAs) were produced which allow the straight-forward assessment of dose within and peripheral to the CT scanned volume. The tables should be useful for medical physicists and radiologists in the estimation of dose to sites beyond the edge of the CT scanned volume.
有时需要评估对内部器官、胚胎或胎儿的辐射剂量,以便进行风险评估或比较影像学研究。资源有限阻碍了准确评估计算机断层扫描(CT)期间实际扫描组织体积之外部位所接受辐射剂量的能力。本研究的目的是评估外周剂量并提供用于剂量评估的表格数据。采用经过验证的蒙特卡罗模拟技术来计算沿直径为16厘米和32厘米的水等效圆柱形模体长度的剂量分布。为了进一步验证,对物理测量的空气比释动能曲线和蒙特卡罗模拟得出的曲线进行了比较,结果显示二者具有极佳的(1%至2%)一致性。研究了带有射束整形滤波器的80、100、120和140千伏峰值的多能X射线光谱。将10⁸个模拟光子垂直于圆柱体的长轴输入圆柱体,在圆柱体的三个深度(中心、中间深度和表面)确定剂量分布的线扩展函数(LSF)。然后将LSF数据运用适当的数学方法来计算沿圆柱体长轴的剂量分布。螺旋扫描(螺距 = 1.0)和轴向扫描产生的剂量分布大致相同。在距CT扫描组织体积边缘约3厘米以外,辐射剂量呈指数下降。编制了一系列以100毫安秒(mAs)归一化的表格,可直接评估CT扫描体积内及外周的剂量。这些表格对于医学物理学家和放射科医生估计CT扫描体积边缘以外部位的剂量应会有所帮助。