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Alkyl Mercury-Induced Toxicity: Multiple Mechanisms of Action.烷基汞诱导的毒性：多种作用机制
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The cellular force-frequency response in ventricular myocytes from the varanid lizard, Varanus exanthematicus.变温动物蜥蜴（Varanus exanthematicus）心室肌细胞的细胞力频率反应。
Am J Physiol Regul Integr Comp Physiol. 2010 Mar;298(3):R567-74. doi: 10.1152/ajpregu.00650.2009. Epub 2010 Jan 6.
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Calcium regulation of single ryanodine receptor channel gating analyzed using HMM/MCMC statistical methods.使用隐马尔可夫模型/马尔可夫链蒙特卡罗统计方法分析单个兰尼碱受体通道门控的钙调节。
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8
Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release.心脏钙火花的终止：钙诱导钙释放的研究性数学模型
Biophys J. 2002 Jul;83(1):59-78. doi: 10.1016/s0006-3495(02)75149-7.

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Response.反应
Science. 1994 Feb 18;263(5149):987-8. doi: 10.1126/science.263.5149.987.
2
Markovian models of low and high activity levels of cardiac ryanodine receptors.心脏兰尼碱受体低活性和高活性水平的马尔可夫模型。
Biophys J. 2001 Jun;80(6):2727-41. doi: 10.1016/S0006-3495(01)76241-8.
3
Rapid activation of the cardiac ryanodine receptor by submillisecond calcium stimuli.亚毫秒级钙刺激对心肌兰尼碱受体的快速激活。
J Gen Physiol. 1999 Dec;114(6):787-98. doi: 10.1085/jgp.114.6.787.
4
Ca2+ spark termination: inactivation and adaptation may be manifestations of the same mechanism.钙离子火花终止：失活和适应性可能是同一机制的表现。
J Gen Physiol. 1999 Jul;114(1):163-6. doi: 10.1085/jgp.114.1.163.
5
Termination of Ca2+ release by a local inactivation of ryanodine receptors in cardiac myocytes.心肌细胞中兰尼碱受体局部失活导致钙离子释放终止。
Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):15096-101. doi: 10.1073/pnas.95.25.15096.
6
The interactions of ATP, ADP, and inorganic phosphate with the sheep cardiac ryanodine receptor.三磷酸腺苷（ATP）、二磷酸腺苷（ADP）和无机磷酸盐与绵羊心脏兰尼碱受体的相互作用。
Biophys J. 1998 Mar;74(3):1296-304. doi: 10.1016/S0006-3495(98)77843-9.
7
Intrasarcomere [Ca2+] gradients and their spatio-temporal relation to Ca2+ sparks in rat cardiomyocytes.大鼠心肌细胞肌节内[Ca2+]梯度及其与Ca2+火花的时空关系。
J Physiol. 1998 Apr 1;508 ( Pt 1)(Pt 1):145-52. doi: 10.1111/j.1469-7793.1998.145br.x.
8
Adaptation of single cardiac ryanodine receptor channels.单个心肌兰尼碱受体通道的适应性
Biophys J. 1997 Feb;72(2 Pt 1):691-7. doi: 10.1016/s0006-3495(97)78705-8.
9
Ryanodine receptor adaptation and Ca2+(-)induced Ca2+ release-dependent Ca2+ oscillations.兰尼碱受体适应性与钙离子诱导的钙离子释放依赖性钙离子振荡
Biophys J. 1996 Dec;71(6):3477-87. doi: 10.1016/S0006-3495(96)79543-7.
10
A minimal gating model for the cardiac calcium release channel.一种用于心脏钙释放通道的最小门控模型。
Biophys J. 1996 Dec;71(6):2996-3012. doi: 10.1016/S0006-3495(96)79492-4.

Do inactivation mechanisms rather than adaptation hold the key to understanding ryanodine receptor channel gating?

作者信息

Sitsapesan R, Williams A J

机构信息

Department of Cardiac Medicine, The National Heart and Lung Institute, Imperial College of Science, Technology and Medicine, London SW3 6LY, United Kingdom.

出版信息

J Gen Physiol. 2000 Dec;116(6):867-72. doi: 10.1085/jgp.116.6.867.

DOI:10.1085/jgp.116.6.867
PMID:11099352
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2231821/
Abstract
摘要