Drenth J P, Nagengast F M
Universitair Medisch Centrum St. Radboud, Kliniek voor Inwendige Ziekten, afd. Maag-, Darm- en Leverziekten, Nijmegen.
Ned Tijdschr Geneeskd. 2000 Nov 18;144(47):2237-40.
Three patients, men aged 67, 68 en 61, had for many years suffered from recurrent iron deficient anaemia and were found to have an aortic stenosis. Coloscopy identified angiodysplastic lesions, and we suspected additional lesions in the small intestine. Despite surgical and endoscopic treatment, gastrointestinal bleeding recurred. Replacement of the stenosed aortic valve with a bioprosthesis led to a recovery in the haemoglobin levels of all three patients. Angiodysplasias are a common source of gastrointestinal bleeding with an invisible origin. Data from the literature suggest an association between aortic stenosis and angiodysplasia although epidemiological evidence is lacking.
三名男性患者,年龄分别为67岁、68岁和61岁,多年来一直患有复发性缺铁性贫血,且被发现患有主动脉瓣狭窄。结肠镜检查发现血管发育异常病变,我们怀疑小肠还有其他病变。尽管进行了手术和内镜治疗,但胃肠道出血仍复发。用生物假体置换狭窄的主动脉瓣后,三名患者的血红蛋白水平均恢复正常。血管发育异常是胃肠道出血的常见隐匿性病因。文献数据表明主动脉瓣狭窄与血管发育异常之间存在关联,尽管缺乏流行病学证据。