Nuñez J L, Juraska J M
Neuroscience Program and Department of Psychology, University of Illinois at Champaign-Urbana, 603 E. Daniel Street, Champaign, IL 61820, USA.
Brain Res Dev Brain Res. 2000 Nov 30;124(1-2):121-4. doi: 10.1016/s0165-3806(00)00093-6.
Neonatal cryoanesthesia has recently been documented to affect morphology and behavior after a single exposure [Dev. Brain Res. 111 (1998) 89; Horm. Behav. 37 (2000) 169]. In the current experiment, we investigated the effect of one-time exposure to halothane inhalant anesthesia on neonatal rats of both sexes. Fifteen minutes of exposure on postnatal day one resulted in detectable changes in the volume of the visual cortex at 3 months. Thus, neonatal halothane alters neural development and its effects are observable in the adult rat.
近期研究表明，单次暴露于新生儿冷冻麻醉会影响其形态和行为[《发育脑研究》111 (1998) 89；《激素与行为》37 (2000) 169]。在本实验中，我们研究了一次性暴露于氟烷吸入麻醉对新生雌雄大鼠的影响。出生第一天暴露15分钟后，3个月时可检测到视皮层体积的变化。因此，新生儿氟烷会改变神经发育，且其影响在成年大鼠中也可观察到。
