Smolens I A, Pagani F D, Bolling S F
The University of Michigan, Section of Cardiac Surgery, Taubman Health Care Center, 2120D, Box 0348, 1500 E Medical Center Drive, Ann Arbor, MI 48109-0348, USA.
Eur J Heart Fail. 2000 Dec;2(4):365-71. doi: 10.1016/s1388-9842(00)00125-2.
Mitral regurgitation (MR) is a frequent complication of end-stage heart failure. Historically, these patients were either managed medically or with mitral valve replacement, both associated with poor outcomes. Mitral valve repair via an 'undersized' annuloplasty repair is safe and effectively corrects MR in heart-failure patients. All of the observed changes contribute to reverse remodeling and restoration of the normal left-ventricular geometric relationship. Mitral valve repair offers a new strategy for patients with MR and end-stage heart failure.
二尖瓣反流（MR）是终末期心力衰竭的常见并发症。从历史上看，这些患者要么接受药物治疗，要么进行二尖瓣置换术，但这两种治疗方式的预后都很差。通过“尺寸过小”的瓣环成形术进行二尖瓣修复对心力衰竭患者来说是安全有效的，能够纠正二尖瓣反流。所有观察到的变化都有助于逆向重塑和恢复正常的左心室几何关系。二尖瓣修复为患有二尖瓣反流和终末期心力衰竭的患者提供了一种新的治疗策略。
