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在门诊寻求医疗帮助的患者中的心力衰竭。第一部分。一般特征。

Heart failure in patients seeking medical help at outpatients clinics. Part I. General characteristics.

作者信息

Rywik S L, Wagrowska H, Broda G, Sarnecka A, Pytlak A, Polakowska M, Drewla J, Korewicki J

机构信息

Department of Epidemiology and Prevention of Cardiovascular Disease, Stefan Cardinal Wyszyński National Institute of Cardiology, 04-628 Warsaw, Alpejska 42, Poland.

出版信息

Eur J Heart Fail. 2000 Dec;2(4):413-21. doi: 10.1016/s1388-9842(00)00106-9.

Abstract

BACKGROUND

During the last decade, the beneficial changes in lifestyle and in medical care increased average life expectancy, particularly in patients with chronic diseases such as hypertension and coronary heart disease. Unfortunately this also increased the number of patients, particularly among the elderly, who are susceptible to complications of these conditions such as heart failure. Uncontrolled hypertension is known to be a primary cause of heart failure and is also known to be very prevalent and frequently uncontrolled in the Polish population.

AIM

To estimate the prevalence and characteristics of heart failure among patients of 65 years and older seeking medical care in outpatient clinics in Poland.

METHODS

The study is a cross-country epidemiological project in which 417 physicians from outpatient clinics were asked to register 50 consecutive patients aged 65 years and above seeking medical care for any cause. Information on case history, physical examination (diagnosis of heart failure, NYHA class, heart failure symptoms), laboratory tests (resting ECG, chest X-ray, echocardiogram) and data concerning pharmacology management during the 2 weeks prior to the index visit was obtained.

RESULTS

Over 5 months, 19877 eligible patients (7324 men and 12553 women) presented to the 417 participating physicians (90% physicians registered 46-50 patients). Among the patients, 53% were diagnosed with heart failure (3901 men and 6678 women), prevalence did not differ by gender. Among patients with heart failure there were 38% of men in NYHA class III or IV and 34% of women. Coronary heart disease was a predominant cause of heart failure in 87% of men (26% of cases with isolated coronary heart disease, 53% with concomitant hypertension and 8% with other diseases), while percentages for women were 80% (15%, 61% and 4%, respectively). Isolated hypertension was a further cause of heart failure in 8% of men and 13% of women. Cardiac arrhythmia was found in approximately 20% of patients, enlargement of heart size in 32% of patients and peripheral leg edema in 54% of men and 64% of women. These symptoms increased with age. Chest X-ray revealed cardiomegaly in 68% of men and women and increased cardiothoracic ratio (>50%) in approximately 40% of patients. From resting ECGs, cardiac arrhythmia was recorded in 21% of patients with heart failure, with atrial fibrillation as a predominant disorder (19%). Left ventricular hypertrophy on resting ECG was noted in 42% of men and women and old myocardial infarction or cardiac ischemia was diagnosed in 71% of men and 66% of women.

CONCLUSIONS

(1) Heart failure was diagnosed in over half of outpatients aged 65 and older; in more than a third of these it was NYHA class III and IV. (2) Outpatients with heart failure had a high frequency of co-existing diseases such as arrhythmia, coronary heart disease and hypertension.

摘要

背景

在过去十年中,生活方式和医疗保健方面的有益变化提高了平均预期寿命,尤其是在患有高血压和冠心病等慢性病的患者中。不幸的是,这也增加了患者数量,特别是在老年人中,他们易患这些疾病的并发症,如心力衰竭。已知未控制的高血压是心力衰竭的主要原因,并且在波兰人群中也非常普遍且经常未得到控制。

目的

评估在波兰门诊寻求医疗护理的65岁及以上患者中心力衰竭的患病率和特征。

方法

该研究是一项跨国流行病学项目,要求来自门诊的417名医生连续登记50名65岁及以上因任何原因寻求医疗护理的患者。获取了关于病史、体格检查(心力衰竭诊断、纽约心脏协会分级、心力衰竭症状)、实验室检查(静息心电图、胸部X光、超声心动图)以及索引就诊前2周内药物治疗管理的数据。

结果

在5个多月的时间里,19877名符合条件的患者(7324名男性和12553名女性)就诊于417名参与研究的医生处(90%的医生登记了46 - 50名患者)。在这些患者中,53%被诊断为心力衰竭(3901名男性和6678名女性),患病率在性别上无差异。在心力衰竭患者中,38%的男性和34%的女性为纽约心脏协会III级或IV级。冠心病是87%男性心力衰竭的主要原因(26%为孤立性冠心病病例,53%伴有高血压,8%伴有其他疾病),而女性的相应比例为80%(分别为15%、61%和4%)。孤立性高血压是8%的男性和13%女性心力衰竭的另一个原因。约20%的患者存在心律失常,32%的患者心脏扩大,54%的男性和64%的女性出现下肢外周水肿。这些症状随年龄增加而增多。胸部X光显示68%的男性和女性存在心脏扩大,约40%的患者心胸比率增加(>50%)。从静息心电图来看,21%的心力衰竭患者记录有心律失常,以心房颤动为主(19%)。静息心电图显示42%的男性和女性存在左心室肥厚,71%的男性和66%的女性被诊断为陈旧性心肌梗死或心肌缺血。

结论

(1)65岁及以上门诊患者中超过一半被诊断为心力衰竭;其中超过三分之一为纽约心脏协会III级和IV级。(2)心力衰竭门诊患者常伴有心律失常、冠心病和高血压等多种疾病。

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