Baccetti T
Department of Orthodontics, University of Florence, Italy.
Angle Orthod. 1998 Oct;68(5):471-4. doi: 10.1043/0003-3219(1998)068<0471:TRAWAO>2.3.CO;2.
The prevalence of tooth rotation concomitant with aplasia of nonadjacent teeth in uncrowded, nonsyndromic subjects was assessed. The sample consisted of 1620 subjects (mean age 14 years 9 months). The findings were compared with the prevalence calculated for a matched control group of 1000 subjects. Rotation of maxillary lateral incisors in subjects with premolar aplasia and rotation of premolars in subjects presenting with maxillary lateral incisor aplasia were studied. Associations between both tooth position anomalies and tooth aplasia were significant (p < 0.01). In addition, the presence of rotated maxillary lateral incisors was also associated with aplasia of the homologous tooth on the opposite side of the dental arch; the same result was found for premolars. These data suggest a genetic component in the etiology of tooth malpositions, such as tooth rotation, which may be considered a covariable in a complex of genetically controlled dental disturbances, including tooth aplasia.
评估了无牙列拥挤、非综合征性受试者中牙齿旋转合并非相邻牙齿发育不全的患病率。样本包括1620名受试者（平均年龄14岁9个月）。将研究结果与为1000名匹配对照组受试者计算的患病率进行比较。研究了前磨牙发育不全受试者中上颌侧切牙的旋转情况以及上颌侧切牙发育不全受试者中前磨牙的旋转情况。两种牙齿位置异常与牙齿发育不全之间的关联均具有显著性（p < 0.01）。此外，上颌侧切牙旋转的存在还与牙弓对侧同源牙的发育不全有关；前磨牙也有相同的结果。这些数据表明牙齿错位（如牙齿旋转）的病因中存在遗传因素，牙齿旋转可能被视为包括牙齿发育不全在内的一组基因控制的牙齿紊乱中的一个协变量。
