Chinn S
Department of Public Health Sciences, King's College, London, 5th floor, Capital House, 42 Weston Street, London SE1 3QD, UK.
Stat Med. 2000 Nov 30;19(22):3127-31. doi: 10.1002/1097-0258(20001130)19:22<3127::aid-sim784>3.0.co;2-m.
A systematic review may encompass both odds ratios and mean differences in continuous outcomes. A separate meta-analysis of each type of outcome results in loss of information and may be misleading. It is shown that a ln(odds ratio) can be converted to effect size by dividing by 1.81. The validity of effect size, the estimate of interest divided by the residual standard deviation, depends on comparable variation across studies. If researchers routinely report residual standard deviation, any subsequent review can combine both odds ratios and effect sizes in a single meta-analysis when this is justified.
系统评价可能涵盖连续结果中的比值比和均值差。对每种类型的结果进行单独的荟萃分析会导致信息丢失,并且可能产生误导。研究表明,通过除以1.81,ln(比值比)可以转换为效应量。效应量的有效性,即感兴趣的估计值除以残差标准差,取决于各研究间的可比变异。如果研究人员常规报告残差标准差,那么在合理的情况下,任何后续评价都可以在单个荟萃分析中同时纳入比值比和效应量。