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吸烟者的细支气管上皮。扫描电子显微镜观察

The bronchiolar epithelium in cigarette smokers. Observations with the scanning electron microscope.

作者信息

Ebert R V, Terracio M J

出版信息

Am Rev Respir Dis. 1975 Jan;111(1):4-11. doi: 10.1164/arrd.1975.111.1.4.

DOI:10.1164/arrd.1975.111.1.4
PMID:1111397
Abstract

Observations with the scanning electron microscope were made on the bronchiolar epithelium of 25 lungs removed at surgery. In all but 3 cases, the lungs were removed for a malignant tumor. Abundant ciliated cells were present in all lung specimens. In lungs obtained from nonsmokers, numerous Clara cells were present in the small bronchioles, whereas goblet cells were seen, and in most cases, the Clara cells were infrequent or absent. The evidence for the secretory nature of the Clara cells is discussed as is the possible effect on lung function of alteration in the type of secretory cell in the bronchioles.

摘要

对手术切除的25个肺的细支气管上皮进行了扫描电子显微镜观察。除3例以外,所有肺均因恶性肿瘤而被切除。在所有肺标本中均存在大量纤毛细胞。在从不吸烟者的肺中,小细支气管中有大量克拉拉细胞,而杯状细胞较少见,且在大多数情况下,克拉拉细胞很少或不存在。文中讨论了克拉拉细胞的分泌性质的证据,以及细支气管中分泌细胞类型改变对肺功能可能产生的影响。

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