Benson C B, Genest D R, Bernstein M R, Soto-Wright V, Goldstein D P, Berkowitz R S
Department of Radiology, New England Trophoblastic Disease Center, Division of Gynecologic Oncology, Harvard Medical School and Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, MA, USA.
Ultrasound Obstet Gynecol. 2000 Aug;16(2):188-91. doi: 10.1046/j.1469-0705.2000.00201.x.
Complete hydatidiform moles are now being diagnosed earlier in gestation, thus the clinical presentation and pathologic findings of complete molar pregnancy have changed. We studied the sonographic appearance of first trimester moles and the ability of ultrasound to detect them.
We reviewed the sonographic interpretation and sonograms, when available, from all patients with first trimester complete moles diagnosed at our institution from January 1988 to March 1996.
Of the 24 patients in our study, the mean gestational age at time of the sonogram was 8.7 +/- 2.0 weeks (mean +/- SD) with a range of 5.7-12.3 weeks. The initial sonographic interpretation was a complete mole in 17 (71%) cases, partial mole versus failed pregnancy in two (8%), and failed pregnancy in five (21%) cases. Of the 22 patients with sonograms available for review, interpretation on review of the images was a complete mole in 18 (82%) cases, partial mole versus failed pregnancy in one (5%), and failed pregnancy in three (14%) cases. The typical sonographic appearance of a first trimester complete mole was a complex, echogenic, intra-uterine mass containing many small cystic spaces.
The majority of first trimester complete moles demonstrate a typical ultrasound appearance such that the diagnosis can be made with ultrasound in most cases.
目前完全性葡萄胎在妊娠早期就能被诊断出来，因此完全性葡萄胎的临床表现和病理表现已经发生了变化。我们研究了妊娠早期葡萄胎的超声表现以及超声检测它们的能力。
我们回顾了1988年1月至1996年3月在我们机构诊断为妊娠早期完全性葡萄胎的所有患者的超声解读和超声图像（如有）。
在我们研究的24例患者中，超声检查时的平均孕周为8.7±2.0周（平均±标准差），范围为5.7 - 12.3周。最初的超声解读为17例（71%）为完全性葡萄胎，2例（8%）为部分性葡萄胎与妊娠失败，5例（21%）为妊娠失败。在可用于复查的22例患者的超声图像中，复查图像解读为18例（82%）为完全性葡萄胎，1例（5%）为部分性葡萄胎与妊娠失败，3例（14%）为妊娠失败。妊娠早期完全性葡萄胎的典型超声表现是一个复杂的、回声增强的、宫内肿块，包含许多小囊腔。
大多数妊娠早期完全性葡萄胎表现出典型的超声表现，因此在大多数情况下可以通过超声做出诊断。
