甲型（H3N2）流感流行期间福利养老院中老年人流感疫苗的有效性
Vaccine effectiveness for influenza in the elderly in welfare nursing homes during an influenza A (H3N2) epidemic.
作者信息
Deguchi Y, Takasugi Y, Nishimura K
机构信息
Office of Elderly Affairs and Department of Social Welfare, Osaka Prefectural Government, Osaka city, Japan.
出版信息
Epidemiol Infect. 2000 Oct;125(2):393-7. doi: 10.1017/s0950268899004410.
Influenza vaccine effect on the occurrence and severity of influenza virus infection in a population residing in nursing homes for the elderly was studied as a cohort study during an influenza A (H3N2) epidemic in Japan. Of 22,462 individuals living in 301 welfare nursing homes, 10,739 voluntarily received inactivated, sub-unit trivalent influenza vaccine in a programme supported by the Osaka Prefectural Government. There were statistically significantly fewer cases of influenza, hospital admissions due to severe infection, and deaths due to influenza in the vaccinated cohort compared to the unvaccinated controls. No serious adverse reactions to vaccination were recorded. Thus influenza vaccination is effective for preventing influenza disease in persons aged 65 years and over, and should be an integral part of the care of this population residing in nursing homes.
在日本甲型（H3N2）流感流行期间，作为一项队列研究，对居住在养老院的老年人群中流感疫苗对流感病毒感染的发生和严重程度的影响进行了研究。在301家福利养老院的22462名居民中，有10739人在大阪县政府支持的一项计划中自愿接种了灭活亚单位三价流感疫苗。与未接种疫苗的对照组相比，接种疫苗的队列中流感病例、因严重感染住院以及因流感死亡的人数在统计学上显著减少。未记录到对疫苗的严重不良反应。因此，流感疫苗接种对于预防65岁及以上人群的流感疾病是有效的，并且应该成为居住在养老院的这一人群护理的一个组成部分。
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