Suzuki S, Yoneyama Y, Sawa R, Shin S, Araki T
Department of Obstetrics and Gynecology, Nippon Medical School, Tokyo, Japan.
Hypertens Pregnancy. 2000;19(3):273-9. doi: 10.1081/prg-100101988.
We examined whether maternal body mass index (BMI) during prepregnancy is useful for prediction of maternal preeclampsia in twin pregnancies.
We studied 250 dichorionic twin pregnancies and 3196 singleton pregnancies. Maternal BMI was calculated during prepregnancy in both twin and singleton pregnancies. The incidence of maternal preeclampsia was compared among three groups, low-BMI [< -1.5 standard deviations (SD)], normal-BMI, and high-BMI (> + 1.5 SD) groups, in both singleton and twin pregnancies.
In singleton pregnancies, the incidence of maternal preeclampsia in the high-BMI group was significantly higher than that in the normal-BMI group (p < 0.05). The relative risk by high BMI was 8.5 (95% confidence interval: 5.6-12.0). However, in twin pregnancies, no significant differences were observed in these values.
Body mass index during prepregnancy was not useful for the prediction of preeclampsia in twin pregnancies. Mechanisms other than maternal weight may be associated with the beginning of preeclampsia in twin pregnancies.
我们研究了孕前母体体重指数（BMI）是否有助于预测双胎妊娠中的母体先兆子痫。
我们研究了250例双绒毛膜双胎妊娠和3196例单胎妊娠。在双胎妊娠和单胎妊娠中均计算孕前母体BMI。比较单胎妊娠和双胎妊娠中低BMI（<-1.5标准差[SD]）、正常BMI和高BMI（>+1.5 SD）三组的母体先兆子痫发生率。
在单胎妊娠中，高BMI组的母体先兆子痫发生率显著高于正常BMI组（p<0.05）。高BMI的相对风险为8.5（95%置信区间：5.6-12.0）。然而，在双胎妊娠中，这些值未观察到显著差异。
孕前体重指数对双胎妊娠先兆子痫的预测无用。除母体体重外的其他机制可能与双胎妊娠先兆子痫的发生有关。
