McCoombes J A, Hirst L W, Green W R
Division of Ophthalmology, University of Queensland, Princess Alexandra Hospital, Brisbane, Australia.
Am J Ophthalmol. 2000 Dec;130(6):830-1. doi: 10.1016/s0002-9394(00)00619-x.
To report the successful treatment of conjunctival manifestations of actinic prurigo with topical cyclosporin.
A 12-year-old female with extensive limbal lesions and chronic conjunctivitis secondary to actinic prurigo was treated with topical cyclosporin, and a rapid clinical response was observed.
The patient had the limbal lesions surgically excised. The lesions completely recurred over the first 2 postoperative months. Treatment with topical steroids and vitamin A ointment was unsuccessful. The patient was then treated with cyclosporine 2% drops and a dramatic improvement occurred. Over a 3-month period, the lesions completely resolved.
Cyclosporine eyedrops may be an effective treatment for the conjunctival manifestations of actinic prurigo.