[局部用环孢素治疗眼部光化性瘙痒症]
[Topical cyclosporine in the treatment of ocular actinic prurigo].
作者信息
Ortiz-Castillo J V, Boto-de-los-Bueis A, De-Lucas-Laguna R, Pastor-Nieto B, Peláez-Restrepo N, Fonseca-Sandomingo A
机构信息
Servicio de Oftalmología, Hospital La Paz, 28009 Madrid, Spain.
出版信息
Arch Soc Esp Oftalmol. 2006 Nov;81(11):661-4. doi: 10.4321/s0365-66912006001100009.
CASE REPORT
A 14-year-old girl from Peru suffered severe limbitis and conjunctivitis. She also presented with clinical skin features diagnosed as actinic prurigo (AP). Her symptoms were successfully controlled with sustained topical therapy of 2% Cyclosporine A.
DISCUSSION
AP is an idiopathic photodermatosis that affects mainly the hispanic population of Latin America. There are ocular signs of severe limbitis and conjunctivitis (like atopic keratoconjunctivitis) in 45% of cases. Literature on the subject is very limited and currently topical cyclosporine seems to be the best therapy available.
病例报告
一名来自秘鲁的14岁女孩患有严重的肢体炎和结膜炎。她还表现出被诊断为光化性痒疹（AP）的临床皮肤特征。通过2%环孢素A的持续局部治疗，她的症状得到了成功控制。
讨论
AP是一种特发性光皮肤病，主要影响拉丁美洲的西班牙裔人群。45%的病例存在严重肢体炎和结膜炎的眼部体征（如特应性角结膜炎）。关于该主题的文献非常有限，目前局部用环孢素似乎是可用的最佳治疗方法。
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