Foster E M
Department of Health Policy and Administration, Pennsylvania State University, University Park 16802-4705, USA.
Health Serv Res. 2000 Dec;35(5 Pt 2):1135-58.
To assess the dose-response relationship for outpatient therapy received by children and adolescents-that is, to determine the impact of added outpatient visits on key mental health outcomes (functioning and symptomatology).
DATA SOURCES/STUDY SETTING: The results presented involve analyses of data from the Fort Bragg Demonstration and are based on a sample of 301 individuals using outpatient services.
This article provides estimates of the impact of outpatient therapy based on comparisons of individuals receiving differing treatment doses. Those comparisons involve standard multiple regression analyses as well as instrumental variables estimation. The latter provides a means of adjusting comparisons for unobserved or unmeasured differences among individuals receiving differing doses, differences that would otherwise be confounded with the impact of treatment dose.
DATA COLLECTION/EXTRACTION METHODS: Using structured diagnostic interviews and behavior checklists completed by the child and his or her caretaker, detailed data on psychopathology, symptomatology, and psychosocial functioning were collected on individuals included in these analyses. Information on the use of mental health services was taken from insurance claims and a management information system. Services data were used to describe the use of outpatient therapy within the year following entry into the study.
PRINCIPAL FINDINGS/CONCLUSIONS: Instrumental variables estimation indicates that added outpatient therapy improves functioning among children and adolescents. The effect is statistically significant and of moderate practical magnitude. These results imply that conventional analyses of the dose-response relationship may understate the impact of additional treatment on functioning. This finding is robust to choice of functional form, length of time over which outcomes are measured, and model specification. Dose does not appear to influence symptomatology.
评估儿童和青少年接受门诊治疗的剂量反应关系,即确定增加门诊就诊次数对关键心理健康结果(功能和症状)的影响。
数据来源/研究背景:所呈现的结果涉及对布拉格堡示范项目数据的分析,基于301名使用门诊服务的个体样本。
本文通过比较接受不同治疗剂量的个体,对门诊治疗的影响进行了估计。这些比较包括标准多元回归分析以及工具变量估计。后者提供了一种方法,用于调整接受不同剂量个体之间未观察到或未测量到的差异的比较,否则这些差异会与治疗剂量的影响混淆。
数据收集/提取方法:通过儿童及其照顾者完成的结构化诊断访谈和行为清单,收集了这些分析中个体的详细心理病理学、症状和心理社会功能数据。心理健康服务使用信息来自保险理赔和管理信息系统。服务数据用于描述研究进入后一年内门诊治疗的使用情况。
主要发现/结论:工具变量估计表明,增加门诊治疗可改善儿童和青少年的功能。效果具有统计学意义且实际影响程度适中。这些结果意味着,对剂量反应关系的传统分析可能低估了额外治疗对功能的影响。这一发现对于函数形式的选择、测量结果的时间长度以及模型设定具有稳健性。剂量似乎不影响症状。