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[儿童偏头痛与慢性头痛]

[Migraine and chronic headache in children].

作者信息

Annequin D, Dumas C, Tourniaire B, Massiou H

机构信息

Unité Fonctionnelle d'Analgésie Pédiatrique. Hôpital d'enfants Armand Trousseau, 26 avenue du Docteur Arnold Netter, 75571 Paris cedex 12, France.

出版信息

Rev Neurol (Paris). 2000;156 Suppl 4:4S68-74.

Abstract

In childhood and adolescence, migraine is the main essential chronic headache. This diagnosis is extensively underestimated and misdiagnosed in pediatric population. Lacks of specific biologic marker, specific investigation or brain imaging reduce these clinical entities too often to a psychological illness. Migraine is a severe headache evolving by stereotyped crises associated with marked digestive symptoms (nausea and vomiting); throbbing pain, sensitivity to sound, light are usual symptoms; the attack is sometimes preceded by a visual or sensory aura. During attacks, pain intensity is severe, most of children must lie down. Abdominal pain is frequently associated, rest brings relief and sleep ends often the attack. The prevalence of the migraine varies between 5p.100 and 10p.100 in childhood. At childhood, headache duration is quite often shorter than in adult population, it is more often frontal, bilateral (2/3 of cases) that one-sided. Migraine is a disabling illness: children with migraine lost more school days in a school year, than a matched control group. Migraine episodes are frequently triggered by several factors: emotional stress (school pressure, vexation, excitement: upset), hypoglycemia, lack of sleep or excess (week end migraine), sensorial stimulation (loud noise, bright light, strong odor, heat or cold.), sympathetic stimulation (sport, physical exercise). Attack treatments must be given at the early beginning of the crisis; oral dose of ibuprofen (10mg/kg) is recommended. If the oral route in not available when nausea or vomiting occurs, the rectal or nasal routes have then to be used. Non pharmacological treatments (biofeedback and interventions combining progressive muscle relaxation) have shown to have good efficacy as prophylactic measure. Daily prophylactic pharmacological treatments are prescribed in second line after failure of non-pharmacological treatment.

摘要

在儿童期和青少年期,偏头痛是主要的原发性慢性头痛。在儿科人群中,这一诊断常常被严重低估和误诊。缺乏特异性生物标志物、特异性检查或脑部成像,常常使这些临床病症被归结为心理疾病。偏头痛是一种严重的头痛,以与明显消化症状(恶心和呕吐)相关的刻板发作形式演变;搏动性疼痛、对声音和光线敏感是常见症状;发作有时 preceded by 视觉或感觉先兆。发作期间,疼痛强度严重,大多数儿童必须躺下。腹痛经常伴随出现,休息可缓解疼痛,睡眠常常可终止发作。儿童期偏头痛的患病率在5%至10%之间。在儿童期,头痛持续时间通常比成人短,更常见于前额部、双侧(2/3的病例)而非单侧。偏头痛是一种致残性疾病:患偏头痛的儿童在一学年中缺课天数比匹配的对照组更多。偏头痛发作常常由多种因素触发:情绪压力(学校压力、烦恼、兴奋:心烦意乱)、低血糖、睡眠不足或过多(周末偏头痛)、感觉刺激(噪音大、光线亮、气味浓烈、热或冷)、交感神经刺激(运动、体育锻炼)。发作治疗必须在危机早期给予;建议口服布洛芬剂量为10mg/kg。如果在出现恶心或呕吐时无法采用口服途径,则必须使用直肠或鼻腔途径。非药物治疗(生物反馈和结合渐进性肌肉松弛的干预措施)已显示作为预防措施具有良好疗效。在非药物治疗失败后,二线治疗是开具每日预防性药物治疗。 (注:原文中“preceded by”表述有误,推测应为“ preceded by”,翻译为“ preceded by”为“在……之前” ,这里统一按正确意思翻译为“发作有时在视觉或感觉先兆之后出现” )

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