Zeeman G G, Veth E O, Dennison D K
Department of Obstetrics & Gynecology, University of Texas Southwestern Medical Center, Dallas 75390-9032, USA.
Obstet Gynecol Surv. 2001 Jan;56(1):43-9. doi: 10.1097/00006254-200101000-00024.
A definite relationship is emerging between periodontal infections and systemic conditions. The objective of this review is to address this relationship as it pertains to cardiovascular disease and diabetes mellitus. Furthermore, because recent reports link the presence of periodontal disease to preterm delivery, the possible relationship between the development and progression of periodontal disease and certain hormonal states in women such as puberty, oral contraceptive use, menopause, and pregnancy will also be discussed. Although the current literature suggests a strong association between periodontal disease and a number of the discussed systemic conditions, causality can only be established with prospective studies. Intervention studies are needed to address how treatment effects the incidence and/or severity of periodontal disease-related systemic illness.
牙周感染与全身疾病之间正在显现出一种明确的关系。本综述的目的是阐述这种与心血管疾病和糖尿病相关的关系。此外，由于近期报告将牙周病的存在与早产联系起来，还将讨论牙周病的发生和发展与女性某些激素状态（如青春期、口服避孕药使用、更年期和怀孕）之间的可能关系。尽管当前文献表明牙周病与许多上述全身疾病之间存在密切关联，但因果关系只能通过前瞻性研究来确立。需要进行干预研究，以探讨治疗如何影响与牙周病相关的全身疾病的发病率和/或严重程度。
