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基础步兵训练期间的免疫功能与感染发生率

Immune function and incidence of infection during basic infantry training.

作者信息

Brenner I K, Severs Y D, Rhind S G, Shephard R J, Shek P N

机构信息

Biomedical Sciences Section, Defence and Civil Institute of Environmental Medicine, Toronto, Ontario, Canada M3 M 3B9.

出版信息

Mil Med. 2000 Nov;165(11):878-83.

PMID:11143439
Abstract

The effect of an 18.5-week infantry training program on health status was studied in 23 male military personnel (aged 22.0 +/- 0.5 years, mean +/- SE). Aerobic power, body composition, and immune function (including natural killer cell activity, mitogen-stimulated lymphocyte proliferation, in vivo cell-mediated immunity, and secretory immunoglobulin A levels) were measured in subjects at the beginning and end of the course. Subjects self-reported their symptoms of sickness in health logs using a precoded checklist. Data from this study indicate that subjects became leaner and maintained, but did not increase, their aerobic fitness by the end of the course. Cell function was enhanced significantly; however, in vivo cell-mediated immunity remained the same, and levels of secretory immunoglobulin A were lower by the end of the course. The incidence of infection remained stable throughout the course. These results indicate that the current pattern of infantry training does not have an adverse effect on the health status of recruits.

摘要

对23名男性军事人员(年龄22.0±0.5岁,均值±标准误)进行了一项为期18.5周的步兵训练计划对健康状况影响的研究。在课程开始和结束时对受试者的有氧能力、身体成分和免疫功能(包括自然杀伤细胞活性、丝裂原刺激的淋巴细胞增殖、体内细胞介导免疫和分泌型免疫球蛋白A水平)进行了测量。受试者使用预先编码的检查表在健康日志中自我报告疾病症状。这项研究的数据表明,到课程结束时,受试者变瘦了,有氧适能得以维持但并未提高。细胞功能显著增强;然而,体内细胞介导免疫保持不变,到课程结束时分泌型免疫球蛋白A水平降低。在整个课程中感染发生率保持稳定。这些结果表明,当前的步兵训练模式对新兵的健康状况没有不利影响。

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