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[蜱传脑炎(TBE)患者粒细胞中FcR和CR受体表达及免疫复合物水平的评估]

[Evaluation of FcR and CR receptor expression in granulocytes and immune complex level in patients with tick-borne encephalitis (TBE)].

作者信息

Izycka A, Jabłońska E, Zajkowska J, Hermanowska-Szpakowicz T, Izycki T

机构信息

Zakładu Immunopatologii AM w Białymstoku.

出版信息

Pol Merkur Lekarski. 2000 Oct;9(52):701-3.

PMID:11144061
Abstract

The aim of this study was to estimate expression of FcR and CR membrane receptors of PMN and circulating immune complexes level in serum from infected patients before and after treatment. Before treatment we observed significant decrease of PMN percentage with FcR and CR receptors in comparison to control. After treatment there was increase of PMN percentage with receptors in comparison to values before treatment but it did not reach values of controls. Immune complexes level before treatment was significant higher than controls before treatment and it decreased after treatment but did not reach control level. Depression of phagocytic activity of PMN may be one of the main reasons for spreading viral infection.

摘要

本研究的目的是评估感染患者治疗前后血清中PMN的FcR和CR膜受体表达以及循环免疫复合物水平。治疗前,与对照组相比,我们观察到具有FcR和CR受体的PMN百分比显著降低。治疗后,与治疗前的值相比,具有受体的PMN百分比有所增加,但未达到对照组的值。治疗前免疫复合物水平显著高于治疗前的对照组,治疗后有所下降,但未达到对照水平。PMN吞噬活性的降低可能是病毒感染传播的主要原因之一。

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