Miszczyk L, Spindel J, Trela K, Ficek K
Zakład Radioterapii, Centrum Onkologii-Instytut im. M. Skłodowskiej-Curie, Oddział w Gliwicach.
Chir Narzadow Ruchu Ortop Pol. 2000;65(4):401-7.
The paper presents the analysis of results of treatment with radiotherapy of 14 cases of vertebral hemangiomas. All patients were irradiated in accordance with conventional schedule fractionated doses, using 2 Gy per fraction. The total radiation dose amounted to 20 Gy (1 case), 24 Gy (4 cases) and 30 Gy (9 cases). The degree of pain relief and lesion reossification was assessed 1 months and 6 months after completion of radiotherapy. Complete pain relief 1 month post radiotherapy was noted in 5 cases (on average patients claimed that radiotherapy resulted in a 70% decrease of pain syndromes). Six months post radiotherapy complete pain relief was noted in 8 cases (on average patients reported a 90% decrease in pain). Signs of reossification were observed in cases 6 months after treatment. No correlation was noted neither between the degree of pain relief and reossification, nor between the total delivered dose and the degree of pain relief. The obtained results allow to conclude that conventionally fractionated radiotherapy (using 20-24 Gy as total dose) is a good method of analgetic treatment of vertebral hemangiomas probably based on the anti-inflammatory effect of radiation.
本文介绍了14例椎体血管瘤放射治疗结果的分析。所有患者均按照常规分次剂量放疗方案进行照射，每次分割剂量为2Gy。总辐射剂量分别为20Gy（1例）、24Gy（4例）和30Gy（9例）。在放疗结束后1个月和6个月评估疼痛缓解程度和病变再骨化情况。放疗后1个月有5例患者疼痛完全缓解（平均而言，患者称放疗使疼痛综合征减轻了70%）。放疗后6个月有8例患者疼痛完全缓解（平均而言，患者报告疼痛减轻了90%）。治疗6个月后观察到再骨化迹象。在疼痛缓解程度与再骨化之间，以及总给予剂量与疼痛缓解程度之间均未发现相关性。所得结果表明，常规分割放疗（总剂量为20 - 24Gy）可能基于辐射的抗炎作用，是椎体血管瘤止痛治疗的一种良好方法。
