Winkler C, Dornfeld S, Baumann M, Christen N, Herrmann T, Eberhardt H J
Klinik und Poliklinik für Strahlentherapie, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden.
Strahlenther Onkol. 1996 Dec;172(12):681-4.
Assessment of the efficacy of radiation therapy for symptomatic vertebral hemangiomas.
Records of 19 patients who were treated from 1969 to 1988 were retrospectively analyzed. Radiation treatment was given at 2 Gy per fraction to 20 Gy (n = 2), 30 Gy (n = 11), or 40 Gy (n = 6). Improvement of symptoms was chosen to determine the efficacy of the treatment. In addition the lesions were controlled radiographically.
Symptomatic improvement was achieved in 17 of 19 patients, remission was complete in 7 patients. No dose-response relationship was observed. The median time to improvement of symptoms was 3 months. The radiographic controls did not correlate with the clinical course.
Radiation therapy is an effective treatment for symptomatic vertebral hemangiomas. The aim of the treatment is to ameliorate clinical symptoms, radiographic improvement is of minor importance.
评估放射治疗对有症状的椎体血管瘤的疗效。
回顾性分析了1969年至1988年期间接受治疗的19例患者的记录。放射治疗每次给予2 Gy，总剂量为20 Gy（n = 2）、30 Gy（n = 11）或40 Gy（n = 6）。以症状改善来确定治疗效果。此外，通过影像学检查对病变进行控制。
19例患者中有17例症状得到改善，7例完全缓解。未观察到剂量反应关系。症状改善的中位时间为3个月。影像学检查结果与临床病程无关。
放射治疗是治疗有症状椎体血管瘤的有效方法。治疗的目的是改善临床症状，影像学改善不太重要。
