Savy L, Lloyd G, Lund V J, Howard D
Institute of Laryngology and Otology, University College London, London, UK.
J Laryngol Otol. 2000 Nov;114(11):891-3. doi: 10.1258/0022215001904284.
Inverted papilloma is the most common benign tumour of the nose and paranasal sinuses, and usually arises in the lateral wall of the nasal cavity and the middle meatus. The diagnosis is suggested on computed tomography (CT) when there is a mass continuous from the middle meatus into the adjacent maxillary antrum, through an expanded maxillary ostium. The mass may contain areas of high density or calcification, and there may be sclerosis of the wall of the affected sinus. The main advantage of magnetic resonance imaging (MRI) is in defining the extent of the tumour, and in differentiating it from adjacent inflammatory tissue, but there are no certain signal intensity or enhancement characteristics to help differentiate inverted papilloma from sinus malignancy. In the differential diagnosis, antro-choanal polyp, malignant sinus tumours and chronic rhinosinusitis and fungal disease need to be excluded. The combination of bone deformity and sclerosis with the typical antro-meatal mass suggests a slow-growing tumour such as inverted papilloma.
内翻性乳头状瘤是鼻腔和鼻窦最常见的良性肿瘤，通常发生于鼻腔外侧壁和中鼻道。当计算机断层扫描（CT）显示有肿块从中鼻道经扩大的上颌窦口延续至相邻的上颌窦时，可提示诊断。肿块可能包含高密度或钙化区域，受累鼻窦壁可能出现骨质硬化。磁共振成像（MRI）的主要优势在于确定肿瘤范围以及将其与相邻的炎性组织区分开来，但没有特定的信号强度或强化特征有助于将内翻性乳头状瘤与鼻窦恶性肿瘤区分。在鉴别诊断中，需要排除上颌窦后鼻孔息肉、鼻窦恶性肿瘤、慢性鼻-鼻窦炎和真菌病。骨质畸形和硬化与典型的窦口鼻道肿块相结合提示为生长缓慢的肿瘤，如内翻性乳头状瘤。
