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鼻窦内翻性乳头状瘤与鳞状细胞癌:当代治疗与患者预后

Sinonasal Inverted Papilloma and Squamous Cell Carcinoma: Contemporary Management and Patient Outcomes.

作者信息

Eide Jacob G, Welch Kevin C, Adappa Nithin D, Palmer James N, Tong Charles C L

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Department of Otolaryngology-Head and Neck Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

出版信息

Cancers (Basel). 2022 Apr 28;14(9):2195. doi: 10.3390/cancers14092195.

Abstract

Inverted papillomas (IP) are the most common sinonasal tumor with a tendency for recurrence, potential attachment to the orbit and skull base, and risk of malignant degeneration into squamous cell carcinoma (SCC). While the overall rate of recurrence has decreased with the widespread adoption of high-definition endoscopic optics and advanced surgical tools, there remain challenges in managing tumors that are multiply recurrent or involve vital neurovascular structures. Here, we review the state-of-the-art diagnostic tools for IP and IP-degenerated SCC, contemporary surgical management, and propose a surveillance protocol.

摘要

内翻性乳头状瘤(IP)是最常见的鼻窦肿瘤,具有复发倾向、可能附着于眼眶和颅底以及恶变为鳞状细胞癌(SCC)的风险。虽然随着高清内镜光学设备和先进手术工具的广泛应用,总体复发率有所下降,但在处理多次复发或累及重要神经血管结构的肿瘤时仍存在挑战。在此,我们回顾了IP和IP恶变SCC的最新诊断工具、当代手术治疗方法,并提出了一个监测方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b397/9102473/f2e2a51e85ca/cancers-14-02195-g001.jpg

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