Suppr超能文献

抑郁症很常见,这会妨碍对老年充血性心力衰竭患者的功能状态进行准确评估。

Depression is common and precludes accurate assessment of functional status in elderly patients with congestive heart failure.

作者信息

Skotzko C E, Krichten C, Zietowski G, Alves L, Freudenberger R, Robinson S, Fisher M, Gottlieb S S

机构信息

Department of Psychiatry, University of Medicine and Dentistry New Jersey, Robert Wood Johnson Medical School, New Brunswick 08901, USA.

出版信息

J Card Fail. 2000 Dec;6(4):300-5. doi: 10.1054/jcaf.2000.19222.

Abstract

BACKGROUND

Congestive heart failure (CHF) and depression are independently known to result in physical decline and diminished functional capacity in the general population. The prevalence and relationship of depressive symptoms in CHF to physical limitations has not been objectively examined.

METHODS AND RESULTS

The Center for Epidemiological Studies Depression Scale (CES-D) was used to ascertain depressive symptoms in 33 elderly ambulatory individuals with CHF. Self-report assessment of functional status, cardiopulmonary exercise testing (CPX), and measurement of energy expenditure by doubly labeled water and Caltrac Accelerometer (Muscle Dynamics, Torrance, CA) were performed. Depressed and nondepressed groups were compared. Forty-two percent of the patients scored in the depressed range (CES-D score of 16 or greater). There were no differences in demographic variables or severity of illness between the depressed and nondepressed patients. Energy expenditure was comparable across groups. Although obtaining similar maximal heart rate and maximal oxygen consumption (VO2max) on CPX, the depressed group showed less exertion on exercise testing with a significantly lower respiratory quotient (P = .017).

CONCLUSION

Depressive symptoms were common and unrelated to the severity of CHF. Although depressed individuals tended to report worse physical functioning than nondepressed individuals, objective assessment of energy expenditure was comparable. Depressed patients appear to underestimate their functional ability. Subsequently, inaccurate assessment of functional status may occur.

摘要

背景

充血性心力衰竭(CHF)和抑郁症各自都会导致普通人群身体机能下降和功能能力减弱。CHF患者抑郁症状的患病率及其与身体功能受限的关系尚未得到客观研究。

方法与结果

采用流行病学研究中心抑郁量表(CES-D)对33例老年CHF门诊患者的抑郁症状进行评估。进行了功能状态的自我报告评估、心肺运动试验(CPX),并通过双标记水和Caltrac加速度计(肌肉动力学公司,加利福尼亚州托伦斯市)测量能量消耗。对抑郁组和非抑郁组进行比较。42%的患者CES-D评分在抑郁范围内(CES-D评分≥16)。抑郁组和非抑郁组在人口统计学变量或疾病严重程度方面无差异。各组间能量消耗相当。尽管在CPX上获得了相似的最大心率和最大耗氧量(VO2max),但抑郁组在运动试验中的用力程度较小,呼吸商显著较低(P = 0.017)。

结论

抑郁症状常见且与CHF严重程度无关。尽管抑郁个体往往比非抑郁个体报告的身体功能更差,但能量消耗的客观评估相当。抑郁患者似乎低估了自己的功能能力。随后,可能会出现对功能状态的不准确评估。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验