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心脏病患者的姑息治疗——性别有影响吗?

Palliative Care for People Living With Heart Disease-Does Sex Make a Difference?

作者信息

Sobanski Piotr Z, Krajnik Malgorzata, Goodlin Sarah J

机构信息

Palliative Care Unit and Competence Center, Department of Internal Medicine, Spital Schwyz, Schwyz, Switzerland.

Department of Palliative Care, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.

出版信息

Front Cardiovasc Med. 2021 Feb 5;8:629752. doi: 10.3389/fcvm.2021.629752. eCollection 2021.

Abstract

The distribution of individual heart disease differs among women and men and, parallel to this, among particular age groups. Women are usually affected by cardiovascular disease at an older age than men, and as the prevalence of comorbidities (like diabetes or chronic pain syndromes) grows with age, women suffer from a higher number of symptoms (such as pain and breathlessness) than men. Women live longer, and after a husband or partner's death, they suffer from a stronger sense of loneliness, are more dependent on institutionalized care and have more unaddressed needs than men. Heart failure (HF) is a common end-stage pathway of many cardiovascular diseases and causes substantial symptom burden and suffering despite optimal cardiologic treatment. Modern, personalized medicine makes every effort, including close cooperation between disciplines, to alleviate them as efficiently as possible. Palliative Care (PC) interventions include symptom management, psychosocial and spiritual support. In complex situations they are provided by a specialized multiprofessional team, but usually the application of PC principles by the healthcare team responsible for the person is sufficient. PC should be involved in usual care to improve the quality of life of patients and their relatives as soon as appropriate needs emerge. Even at less advanced stages of disease, PC is an additional layer of support added to disease modifying management, not only at the end-of-life. The relatively scarce data suggest sex-specific differences in symptom pathophysiology, distribution and the requisite management needed for their successful alleviation. This paper summarizes the sex-related differences in PC needs and in the wide range of interventions (from medical treatment to spiritual support) that can be considered to optimally address them.

摘要

个体心脏病的分布在女性和男性之间存在差异,与此平行的是,在特定年龄组之间也存在差异。女性通常比男性在更年长时受到心血管疾病的影响,并且随着合并症(如糖尿病或慢性疼痛综合征)的患病率随年龄增长,女性比男性遭受更多的症状(如疼痛和呼吸急促)。女性寿命更长,在丈夫或伴侣去世后,她们会感到更强烈的孤独感,更依赖机构护理,并且比男性有更多未得到满足的需求。心力衰竭(HF)是许多心血管疾病常见的终末期途径,尽管进行了最佳的心脏病治疗,但仍会导致严重的症状负担和痛苦。现代个性化医疗尽一切努力,包括各学科之间的密切合作,以尽可能有效地减轻这些负担和痛苦。姑息治疗(PC)干预措施包括症状管理、心理社会和精神支持。在复杂情况下,由专门的多专业团队提供这些支持,但通常负责该患者的医疗团队应用PC原则就足够了。一旦出现适当需求,PC就应参与常规护理,以改善患者及其亲属的生活质量。即使在疾病不太严重的阶段,PC也是在疾病改善管理基础上增加的一层支持,而不仅仅是在生命末期。相对稀缺的数据表明,在症状病理生理学、分布以及成功缓解症状所需的必要管理方面存在性别差异。本文总结了PC需求方面的性别差异以及为最佳满足这些需求可考虑的广泛干预措施(从药物治疗到精神支持)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d457/7901984/b2f5ecfa883a/fcvm-08-629752-g0001.jpg

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