分娩时孕妇血清中的补体结合抗体和淋巴细胞毒性抗体。IV. 血清学

Complement fixing and lymphocytotoxic antibodies in serum of pregnant women at delivery. IV. Serology.

作者信息

Nymand G

出版信息

Vox Sang. 1975;28(1):34-41. doi: 10.1111/j.1423-0410.1975.tb02738.x.

DOI:10.1111/j.1423-0410.1975.tb02738.x

Abstract

The paper concerns 275 sera of pregnant women at delivery containing complement fixing platelet antibodies (CFPAb) and/or lymphocytotoxic antibodies (LCTAb). 79 sera contained operationally monospecific antibodies against platelets and/or lymphocytes. 10 sera had only CFPAb, 4 of these were C-fix anti-A. 41 sera had CFPAb and LCTAb, 18 of these were monospecific against platelets and/or lymphocytes. In 224 sera only LCTAb could be demonstrated, 57 were monospecific. Furthermore in 8 of 258 primigravidae, screened for LCTAb 6 months post partum antibodies were detected. Generally the antibodies present at delivery had disappeared or narrowed, but in 3 cases the antibodies were detectable only in the postpartum sample.

摘要

该论文涉及275份分娩时孕妇的血清，这些血清含有补体结合血小板抗体（CFPAb）和/或淋巴细胞毒性抗体（LCTAb）。79份血清含有针对血小板和/或淋巴细胞的操作上单一特异性抗体。10份血清仅有CFPAb，其中4份是C固定抗A。41份血清同时有CFPAb和LCTAb，其中18份对血小板和/或淋巴细胞是单一特异性的。在224份血清中仅能检测到LCTAb，57份是单一特异性的。此外，在258名初产妇中，产后6个月筛查LCTAb时，在8名产妇中检测到了抗体。一般来说，分娩时存在的抗体已经消失或减弱，但在3例中，仅在产后样本中可检测到抗体。