Mulcahy H E, Hennessy E, Connor P, Rhodes B, Patchett S E, Farthing M J, Fairclough P D
Digestive Diseases Research Centre, St Bartholomew's and Royal London School of Medicine and Dentistry, London, UK.
Aliment Pharmacol Ther. 2001 Feb;15(2):217-20. doi: 10.1046/j.1365-2036.2001.00912.x.
Knowledge of sedation trends for upper gastrointestinal endoscopy is important for health service planning, particularly in view of rapidly increasing demands on endoscopy services. However, no data are available on sedation trends in Britain over the past 10 years.
To determine sedation use for routine gastroscopy in a single endoscopy unit between 1989 and 1998.
This was a retrospective study of 9795 consecutive adults (mean age 56 years, range 18-100 years; 4512 females) who had undergone a gastroscopy between 1989 and 1998. Clinical, pharmacological and endoscopic data were retrieved from a computerized database.
Over the 10-year study period, the sedation rate remained constant for patients undergoing therapeutic endoscopy (P=0.99) and those undergoing in-patient diagnostic examinations (P=0.63). In contrast, the sedation rate for out-patient diagnostic endoscopy decreased by 54%, from a high of 70% in 1990 to 32% in 1998 (P < 0.0001). Logistic regression analysis showed that the decline in sedation use was greater in females (P < 0.0001) than males and in procedures performed by non-consultant compared to consultant staff (P=0.01).
If our results form part of a national trend, they will have important implications for cardiopulmonary monitoring strategies, recovery room practices and for complication rates due to the use of sedation for upper gastrointestinal endoscopy.
了解上消化道内镜检查的镇静趋势对于卫生服务规划很重要,尤其是考虑到对内窥镜检查服务的需求迅速增加。然而,过去10年英国尚无关于镇静趋势的数据。
确定1989年至1998年间单个内镜检查单位常规胃镜检查的镇静使用情况。
这是一项对1989年至1998年间连续接受胃镜检查的9795名成年人(平均年龄56岁,范围18 - 100岁;4512名女性)进行的回顾性研究。临床、药理学和内镜检查数据从计算机数据库中检索。
在为期10年的研究期间,接受治疗性内镜检查的患者(P = 0.99)和接受住院诊断检查的患者(P = 0.63)的镇静率保持不变。相比之下,门诊诊断性内镜检查的镇静率下降了54%,从1990年的70%的高位降至1998年的32%(P < 0.0001)。逻辑回归分析表明,女性(P < 0.0001)的镇静使用率下降幅度大于男性,与顾问人员相比,非顾问人员进行的操作中镇静使用率下降幅度更大(P = 0.01)。
如果我们的结果构成全国趋势的一部分,它们将对心肺监测策略、恢复室实践以及上消化道内镜检查使用镇静剂导致的并发症发生率产生重要影响。