Kilmer S L, Garden J M
Laser & Skin Surgery Center of Northern California and the University of California, Sacramento 95816, USA.
Semin Cutan Med Surg. 2000 Dec;19(4):232-44. doi: 10.1053/sder.2000.18363.
Benign pigmented lesions and tattoos are often very responsive to laser treatment. The chromophore in most cases is melanin, although other endogenous and exogenous pigments can be targeted. The chromophore and its distribution in the skin, as well as the underlying biological processes, all help determine the best laser, if any, for a given pigmented lesion. Epidermal lesions respond well to shorter wavelengths (up to 755 nm), whereas for deeper lesions, 694 nm or longer are typically used. The 1,064-nm Nd:YAG laser is best for treating darker skinned individuals. Multicolored tattoos may need several wavelengths to best target individual ink colors.
良性色素沉着病变和纹身通常对激光治疗反应良好。在大多数情况下,发色团是黑色素,不过其他内源性和外源性色素也可作为靶点。发色团及其在皮肤中的分布,以及潜在的生物学过程,都有助于确定针对特定色素沉着病变的最佳激光(若有)。表皮病变对较短波长(高达755纳米)反应良好,而对于较深的病变,通常使用694纳米或更长的波长。1064纳米的钕:钇铝石榴石激光最适合治疗肤色较深的个体。彩色纹身可能需要几种波长才能最好地针对不同的墨水颜色。