科罗拉多州草原田鼠（Microtus ochrogaster）中，微小巴贝斯虫和比氏疏螺旋体通过尖背硬蜱（Ixodes spinipalpis）传播。

Babesia microti and Borrelia bissettii transmission by Ixodes spinipalpis ticks among prairie voles, Microtus ochrogaster, in Colorado.

作者信息

Burkot T R, Schneider B S, Pieniazek N J, Happ C M, Rutherford J S, Slemenda S B, Hoffmeister E, Maupin G O, Zeidner N S

机构信息

Centers for Disease Control and Prevention, Division of Vector-Borne Infectious Diseases, Fort Collins, Colorado 80522-2087, USA.

出版信息

Parasitology. 2000 Dec;121 Pt 6:595-9.

PMID:11155930

Abstract

An endemic transmission cycle of Babesia microti was discovered in Colorado in the foothills of the Rocky Mountains. B. microti were found by PCR in 4 of 25 Ixodes spinipalpis tick pools tested (a 3.2 % minimum infection rate) and in 87% (13 of 15) of Microtus ochrogaster (the prairie vole) spleen and blood samples. Using naturally infected I. spinipalpis collected from wild-caught M. ochrogaster as vectors, B. microti and Borrelia bissettii were successfully transmitted to laboratory-born M. ochrogaster. Neither I. spinipalpis, nor M. ochrogaster (the prairie vole) have been previously reported as a vector or a reservoir host of B. microti. Unlike the east coast of the United States where Peromyscus leucopus is an important reservoir for B. microti, evidence for Peromyscus spp. (neither P. maniculatus nor P. difficilis) as B. microti reservoirs was not found in this study.

摘要

在落基山脉山麓的科罗拉多州发现了微小巴贝斯虫的地方性传播循环。在25个受测的斯氏硬蜱蜱池中，有4个通过聚合酶链式反应检测到微小巴贝斯虫（最低感染率为3.2%），在15只草原田鼠的脾脏和血液样本中，有87%（13只）检测到微小巴贝斯虫。以从野生捕获的草原田鼠身上采集的自然感染的斯氏硬蜱为媒介，微小巴贝斯虫和比氏疏螺旋体成功传播给实验室出生的草原田鼠。此前，斯氏硬蜱和草原田鼠均未被报道为微小巴贝斯虫的媒介或储存宿主。与美国东海岸不同，白足鼠是微小巴贝斯虫的重要储存宿主，而在本研究中未发现鹿鼠属（北美鹿鼠和困难鹿鼠）作为微小巴贝斯虫储存宿主的证据。