Jonescu-Cuypers C, Jacobi P, Konen W, Krieglstein G
Department of Ophthalmology, University of Cologne, Cologne, Germany.
Ophthalmology. 2001 Feb;108(2):254-8. doi: 10.1016/s0161-6420(00)00514-5.
To compare viscocanalostomy, a nonpenetrating procedure for glaucoma treatment, with trabeculectomy.
Randomized controlled trial.
Twenty white subjects (20 eyes) with open-angle glaucoma with no history of surgery were enrolled.
Ten subjects were randomly assigned to viscocanalostomy according to Stegmann's technique and 10 subjects to a modified Cairns trabeculectomy. A complete ophthalmologic examination was performed the day before surgery and postoperatively. Further visits were scheduled monthly for 6 to 8 months after surgery.
Success was defined as intraocular pressure (IOP) between 7 and 20 mmHg, with no medication.
After a mean follow-up of 6 months (range, 6-8 months), success was obtained in 5 of 10 cases in the trabeculectomy group and in no case in the viscocanalostomy group. With Kaplan-Meier's method, subjects with viscocanalostomy showed shorter postoperative IOP-reduction periods than subjects undergoing trabeculectomy.
According to the results of this short-term study, trabeculectomy was more effective than viscocanalostomy in lowering IOP in glaucomatous eyes of white patients.
比较用于青光眼治疗的非穿透性手术粘小管切开术与小梁切除术。
随机对照试验。
招募了20名无手术史的开角型青光眼白人受试者（20只眼）。
10名受试者根据施特格曼技术随机分配接受粘小管切开术，10名受试者接受改良的凯恩斯小梁切除术。术前一天和术后进行了全面的眼科检查。术后6至8个月每月安排进一步复诊。
成功定义为眼压（IOP）在7至20 mmHg之间且无需用药。
平均随访6个月（范围6 - 8个月）后，小梁切除术组10例中有5例成功，粘小管切开术组无一例成功。采用Kaplan-Meier法，接受粘小管切开术的受试者术后眼压降低期比接受小梁切除术的受试者短。
根据这项短期研究的结果，在降低白人青光眼患者眼压方面，小梁切除术比粘小管切开术更有效。
