Dubin L, Amelar R D
Fertil Steril. 1975 Mar;26(3):217-20. doi: 10.1016/s0015-0282(16)40988-x.
Over a ten-year period, surgical correction of varicocele was performed on 504 selected subfertile men. They were followed up for at least one year after surgery. Semen quality was improved in 71% and 55% of the wives became pregnant. Statistically, the results were better in terms of semen quality improvement and pregnancy for patients who had preoperative sperm counts over 10 million/ml (88% improved, 68% pregnancy rate) than for patients who had preoperative sperm counts of less than 10 million/ml (33% improved, 23% pregnancy rate). The empirical use of postoperative human chorionic gonadotropin therapy in this latter group improved results significantly (56% improved, 44% pregnancy rate).
在十年期间，对504名经挑选的不育男性进行了精索静脉曲张手术矫正。术后对他们进行了至少一年的随访。71%的患者精液质量得到改善，55%的患者妻子怀孕。从统计学角度来看，术前精子计数超过1000万/毫升的患者在精液质量改善和怀孕方面的结果（88%精液质量改善，68%怀孕率）优于术前精子计数低于1000万/毫升的患者（33%精液质量改善，23%怀孕率）。后一组患者术后经验性使用人绒毛膜促性腺激素治疗显著改善了结果（56%精液质量改善，44%怀孕率）。
