Brown J S
Fertil Steril. 1976 Sep;27(9):1046-53.
During a 10-year period 295 varicocelectomies were performed in subfertile males. Results of follow-up studies indicate the following: (1) Semen quality improved in a meaningful manner in 58% of men following varicocelectomy. The improvement, except at times for motility, was often only modest. The semen improved in 46% of men with a preoperative average count of less than 10 million/ml and in 70% whose count was 10 million/ml or more. (2) The stress pattern of sperm morphology was seen prior to surgery in 93% of the men. (3) The pregnancy rate for the entire series was about 41%. Men with a preoperative count of 10 million/ml or more achieved a 48% conception rate and those with a count of less than 10 million/ml succeeded 35% of the time. Only 7% of the pregnancies occurred without a concomitant improvement in the semen quality. (4) Men with moderate- and large-sized left varicoceles fared better than those with small-sized varicoceles. (5) Varicocelectomy, when varicocele and poor semen quality coexist, is a justified procedure in the treatment of the infertile couple.
在10年期间，对295名不育男性进行了精索静脉曲张切除术。随访研究结果表明：（1）58%的男性在精索静脉曲张切除术后精液质量有显著改善。除了有时活力方面，这种改善通常较为有限。术前平均精子计数低于1000万/毫升的男性中，46%的精液质量得到改善；精子计数为1000万/毫升或更高的男性中，70%的精液质量得到改善。（2）93%的男性在手术前出现精子形态的应激模式。（3）整个系列的妊娠率约为41%。术前精子计数为1000万/毫升或更高的男性受孕率为48%，精子计数低于1000万/毫升的男性受孕率为35%。只有7%的妊娠在精液质量没有相应改善的情况下发生。（4）左侧中度和重度精索静脉曲张的男性比轻度精索静脉曲张的男性效果更好。（5）当精索静脉曲张与精液质量差同时存在时，精索静脉曲张切除术是治疗不育夫妇的合理手术。
