Weiner S, Wright K H, Wallach E E
Fertil Steril. 1975 Apr;26(4):363-8.
The described method for selective sympathetic denervation of the in vivo rabbit ovary involved stripping the ovarian artery of its nerve bundles and adventitial tissue. The ovary was then entirely free of fluorescent-staining adrenergic nerves. This technique was used to study the effects of ovarian denervation on HCG-induced ovulation. After HCG was administered to 22 rabbits which had previously undergone unilateral ovarian denervation, the ovaries were observed for follicular maturation and rupture. Control ovaries demonstrated a mean of 5.6 stimulated follicles/ovary; denervated ovaries had a mean of 5.4. An average of 3.5 follicles/control ovary ruptured; an average of 3.1 follicles/denervated ovary ruptured. Furthermore, the time course of ovulation after HCG did not differ between denervated and intact ovaries. These results indicate that HCG-induced ovulation in the rabbit is not interrupted by ovarian denervation.
所述的用于对体内兔卵巢进行选择性交感神经去神经支配的方法包括剥离卵巢动脉的神经束和外膜组织。然后卵巢完全没有荧光染色的肾上腺素能神经。该技术用于研究卵巢去神经支配对人绒毛膜促性腺激素（HCG）诱导排卵的影响。对22只先前接受过单侧卵巢去神经支配的兔子注射HCG后，观察卵巢的卵泡成熟和破裂情况。对照卵巢平均每个卵巢有5.6个受刺激卵泡；去神经支配的卵巢平均有5.4个。对照卵巢平均每个有3.5个卵泡破裂；去神经支配的卵巢平均每个有3.1个卵泡破裂。此外，去神经支配的卵巢和完整卵巢在注射HCG后的排卵时间进程没有差异。这些结果表明，兔体内HCG诱导的排卵不会因卵巢去神经支配而中断。
