Weiner S, Wright K H, Wallach E E
Am J Obstet Gynecol. 1977 May 15;128(2):154-60. doi: 10.1016/0002-9378(77)90679-2.
Two techniques were used to study the neuromuscular control of rabbit ovarian contractions. First, the ovary was denervated by stripping its artery. Spontaneous contractions were noted, as was a normal response to exogenously administered adrenergic agents. Second, the ovarian nerves were electrically stimulated in an in vitro perfused ovary system. Inhibition of ovarian contractions was noted, and the additive effects with adrenergic agents suggested a betamimetic effect of nerve stimulation in the estrous rabbit. After administration of exogenous human chorionic gonadotropin, the response was reversed. The significance of the contribution of a neuromuscular mechanism to the control of ovulation is discussed.
采用两种技术研究兔卵巢收缩的神经肌肉控制。首先，通过剥离卵巢动脉使其去神经支配。观察到自发收缩，以及对外源性给予的肾上腺素能药物的正常反应。其次，在体外灌注卵巢系统中对卵巢神经进行电刺激。观察到卵巢收缩受到抑制，并且与肾上腺素能药物的相加作用表明发情期兔的神经刺激具有拟β效应。给予外源性人绒毛膜促性腺激素后，反应发生逆转。讨论了神经肌肉机制对排卵控制的贡献的意义。
