Weiner S, Wright K H, Wallach E E
Fertil Steril. 1975 Nov;26(11):1083-7. doi: 10.1016/s0015-0282(16)41474-3.
Following unilateral ovarian denervation by ovarian artery stripping in female rabbits, ovulation and pregnancy were achieved within 3 days of denervation. Three weeks later, at repeat laparotomy, ovarian dimensions and the numbers of corpora lutea and pregnancies were noted. Fluorescent histochemical studies confirmed complete adrenergic denervation in five of the rabbits' ovaries. There was no significant difference in ovarian dimensions, numbers of corpora lutea and pregnancies, or the excess of corpora lutea over implantations when the intact control side was compared with the denervated side. The control ovaries demonstrated an average of 5 corpora lutea/ovary and an average of 3.4 conceptuses in the adjacent uterine horn, while the numbers on the denervated side were 5 and 3.2, respectively. Although these findings demonstrate that central neural efferent control is not essential for the occurrence of pregnancy after mating in the rabbit, the potential significance of ovarian neuromuscular mechanisms in these functions is discussed, and future studies are suggested.
在对雌性兔子进行卵巢动脉剥离单侧卵巢去神经支配后，去神经支配后3天内实现了排卵和妊娠。三周后，再次开腹手术时，记录卵巢大小、黄体数量和妊娠情况。荧光组织化学研究证实了五只兔子卵巢中完全的肾上腺素能去神经支配。当将完整的对照侧与去神经支配侧进行比较时，卵巢大小、黄体数量和妊娠情况，或黄体数量超过着床数量方面均无显著差异。对照卵巢平均每个卵巢有5个黄体，相邻子宫角平均有3.4个孕体，而去神经支配侧的数量分别为5个和3.2个。尽管这些发现表明中枢神经传出控制对于兔子交配后妊娠的发生并非必不可少，但仍讨论了卵巢神经肌肉机制在这些功能中的潜在意义，并提出了未来的研究方向。
