Gust D, Moore T A, Moore A L
Department of Chemistry and Biochemistry, Center for the Study of Early Events in Photosynthesis, Arizona State University, Tempe, Arizona 85287, USA.
Acc Chem Res. 2001 Jan;34(1):40-8. doi: 10.1021/ar9801301.
Increased understanding of photosynthetic energy conversion and advances in chemical synthesis and instrumentation have made it possible to create artificial nanoscale devices and semibiological hybrids that carry out many of the functions of the natural process. Artificial light-harvesting antennas can be synthesized and linked to artificial reaction centers that convert excitation energy to chemical potential in the form of long-lived charge separation. Artificial reaction centers can form the basis for molecular-level optoelectronic devices. In addition, they may be incorporated into the lipid bilayer membranes of artificial vesicles, where they function as components of light-driven proton pumps that generate transmembrane proton motive force. The proton gradient may be used to synthesize adenosine triphosphate via an ATP synthase enzyme. The overall energy transduction process in the liposomal system mimics the solar energy conversion system of a photosynthetic bacterium. The results of this research illustrate the advantages of designing functional nanoscale devices based on biological paradigms.
对光合能量转换的深入理解以及化学合成和仪器技术的进步，使得制造出能够执行许多自然过程功能的人工纳米级装置和半生物杂种成为可能。可以合成人工光捕获天线，并将其与人工反应中心相连，这些反应中心将激发能转化为长寿命电荷分离形式的化学势。人工反应中心可以构成分子级光电器件的基础。此外，它们可以被整合到人工囊泡的脂质双分子层膜中，在那里它们作为光驱动质子泵的组件发挥作用，产生跨膜质子动力。质子梯度可通过ATP合酶用于合成三磷酸腺苷。脂质体系统中的整体能量转导过程模拟了光合细菌的太阳能转换系统。这项研究的结果说明了基于生物学范式设计功能性纳米级装置的优势。
