Raison-Peyron N, Meunier L, Vian L, Meynadier J
Service de Dermatologie, Allergologie et Photobiologie, Hôpital Saint-Eloi, Montpellier.
Ann Dermatol Venereol. 2000 Dec;127(12):1083-6.
Contact dermatitis to henna are rarely reported. Most of the time, they are related to additives, especially scented oils or paraphenylene diamine. This latter substance is added to shorten the time of application and to enhance the darkness of the color. We report one case of an allergic contact dermatitis to henna skin tattoo, probably related to a paraphenylene diamine derivative.
A 25-year-old woman developed an allergic contact dermatitis at the site of application of two henna skin tattoos on her right arm. She never dyed her hair and wore dark clothing without problems. Epicutaneous tests were positive for henna paste, paraphenylene diamine, N-isopropyl-N'phenylparaphenylene diamine and five chemical dyes, probably related to cross- reactions between paraphenylene diamine and these dyes. Epicutaneous test with henna powder was negative, confirming the absence of allergy to henna. Fluorescence analysis detected the presence of a primary amine in henna paste but high performance liquid chromatography analysis did not reveal the presence of paraphenylene diamine or any suspect dye. An another allergen, related compound of paraphenylene diamine, was probably present but we failed to identify it with precision.
Labile henna skin tattoos are in fashion at the moment in western European countries. They can be a secrete source of paraphenylene diamine, or one of its related compounds, sensitization.
对指甲花的接触性皮炎鲜有报道。大多数情况下，它们与添加剂有关，尤其是香油或对苯二胺。添加后一种物质是为了缩短涂抹时间并加深颜色。我们报告一例因指甲花皮肤纹身引起的过敏性接触性皮炎，可能与一种对苯二胺衍生物有关。
一名25岁女性在右臂两处指甲花皮肤纹身的涂抹部位发生过敏性接触性皮炎。她从未染过头发，穿深色衣服也没有问题。斑贴试验显示指甲花糊剂、对苯二胺、N -异丙基 - N' -苯基对苯二胺和五种化学染料呈阳性，可能与对苯二胺和这些染料之间的交叉反应有关。指甲花粉的斑贴试验为阴性，证实对指甲花不过敏。荧光分析检测到指甲花糊剂中存在伯胺，但高效液相色谱分析未发现对苯二胺或任何可疑染料的存在。可能存在另一种与对苯二胺相关的过敏原，但我们未能精确识别它。
目前不稳定的指甲花皮肤纹身在西欧国家很流行。它们可能是对苯二胺或其相关化合物致敏的一个隐秘来源。
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