Tunkel D E, Erozan Y S, Weir E G
Department of Otolaryngology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Arch Pathol Lab Med. 2001 Feb;125(2):278-81. doi: 10.5858/2001-125-0278-ECTT.
Cervical thymic masses are congenital lesions that result from aberrant thymic migration during embryogenesis. Although most of these masses are asymptomatic, they may cause debilitating symptoms secondary to encroachment on adjacent aerodigestive structures. Preoperative diagnosis of ectopic thymic tissue is rare; most cases are clinically misinterpreted as branchial cleft remnants or cystic hygromas. Definitive diagnosis has relied on histopathologic examination in nearly all reported cases. However, the invasiveness of open incisional or excisional biopsy carries the risk of surgical and anesthetic complications. Inadvertent surgical thymectomy may result in cell-mediated immune deficiencies in infants and young children. The utility of fine needle aspiration is gaining wider acceptance in the diagnostic evaluation of neck masses. We describe an infant with an asymptomatic cervical thymic mass diagnosed by fine needle aspiration.
颈部胸腺肿物是先天性病变,由胚胎发育过程中胸腺异常迁移所致。尽管这些肿物大多无症状,但因侵犯相邻的气道消化道结构,可能导致使人虚弱的症状。术前诊断异位胸腺组织的情况罕见;大多数病例在临床上被误诊为鳃裂残余或囊性水瘤。几乎所有报道的病例中,确诊都依赖于组织病理学检查。然而,开放性切开活检或切除活检的侵入性会带来手术和麻醉并发症的风险。意外的手术切除胸腺可能导致婴幼儿细胞介导的免疫缺陷。细针穿刺抽吸在颈部肿物的诊断评估中的应用正得到更广泛的认可。我们描述了一名通过细针穿刺抽吸诊断出无症状颈部胸腺肿物的婴儿。