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尿动力学压力流研究可以预测经尿道前列腺切除术后的临床结果。

Urodynamic pressure flow studies can predict the clinical outcome after transurethral prostatic resection.

作者信息

Rodrigues P, Lucon A M, Freire G C, Arap S

机构信息

Department of Urology, Hospital das Clínicas of Univesity of São Paulo, São Paulo, Brazil.

出版信息

J Urol. 2001 Feb;165(2):499-502. doi: 10.1097/00005392-200102000-00033.

Abstract

PURPOSE

We evaluate whether urodynamic evaluation can determine preoperatively the clinical prognosis of patients treated with transurethral prostatic resection as measured by urinary symptom score and quality of life index.

MATERIALS AND METHODS

A total of 253 patients who previously elected transurethral prostatic resection based on clinical symptoms completed the American Urological Association symptom score and quality of life index, and underwent urodynamic evaluation before and after operation. The patients were divided into 7 groups in accordance with detrusor pressure at maximum urinary flow rate. The preoperative and postoperative symptom score and quality of life index were analyzed in each group.

RESULTS

Of the patients 42% were not obstructed and could not be distinguished from those who were obstructed preoperatively based on total urinary symptoms (p = 0.95) or subjective impression measured by the quality of life index (p = 0.96). The entire obstructed group demonstrated marked improvement compared to the nonobstructed group (p = 0.018). Analysis of severity also revealed a clear relationship with clinical outcome and subjective satisfaction with obstruction grade, that is the more severely obstructed cases had greater clinical benefit compared to those with little or no obstruction. Furthermore, the nonobstructed subjects did not show any clinical or subjective improvement after transurethral prostatic resection (p = 0.24).

CONCLUSIONS

Urodynamic studies provide great predictive value of clinical improvement after prostatic relief but they also properly predict the poor clinical results in nonobstructed patients.

摘要

目的

我们评估尿动力学评估能否在术前确定经尿道前列腺切除术后患者的临床预后,该预后通过排尿症状评分和生活质量指数来衡量。

材料与方法

共有253例此前根据临床症状选择经尿道前列腺切除术的患者完成了美国泌尿外科协会症状评分和生活质量指数评估,并在手术前后接受了尿动力学评估。根据最大尿流率时的逼尿肌压力将患者分为7组。对每组患者术前和术后的症状评分及生活质量指数进行分析。

结果

42%的患者不存在梗阻,根据总排尿症状(p = 0.95)或生活质量指数所衡量的主观印象(p = 0.96),无法将其与术前存在梗阻的患者区分开来。与非梗阻组相比,整个梗阻组均表现出明显改善(p = 0.018)。严重程度分析还显示,临床结局与梗阻分级的主观满意度之间存在明确关系,即与梗阻程度较轻或无梗阻的患者相比,梗阻程度越严重的患者临床获益越大。此外,非梗阻患者经尿道前列腺切除术后未表现出任何临床或主观改善(p = 0.24)。

结论

尿动力学研究对前列腺减压术后的临床改善具有很大的预测价值,但它们也能准确预测非梗阻患者的不良临床结果。

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