Tittel J N, Steller H
Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Genome Biol. 2000;1(3):REVIEWS0003. doi: 10.1186/gb-2000-1-3-reviews0003. Epub 2000 Sep 13.
Key components of the programmed cell death pathway are conserved between Caenorhabditis elegans, Drosophila melanogaster and humans. The search for additional homologs has been facilitated by the availability of the entire genomic sequence for each of these organisms.
程序性细胞死亡途径的关键组成部分在秀丽隐杆线虫、黑腹果蝇和人类之间是保守的。这些生物体各自完整基因组序列的可得性促进了对其他同源物的寻找。