静脉注射造影剂后肝细胞癌肿瘤血管的定量比较：传统与谐波能量多普勒超声对比

Quantitative comparison of tumor vascularity of hepatocellular carcinoma after intravenous contrast agent: conventional versus harmonic power Doppler US.

作者信息

Park S H, Kim T K, Lee K H, Kim A Y, Choi J I, Han J K, Choi B I

机构信息

Department of Radiology and the Institute of Radiation Medicine, Seoul National University College of Medicine, 28, Yongon-dong, Chongno-gu, Seoul 110-744, Korea.

出版信息

Abdom Imaging. 2001 Mar-Apr;26(2):178-83. doi: 10.1007/s002610000129.

DOI:10.1007/s002610000129

PMID:11178696

Abstract

BACKGROUND

The purpose of this study was to make a quantitative comparison between conventional and harmonic power Doppler (PD) ultrasound (US) in depicting vascularity of hepatocellular carcinoma (HCC).

METHODS

Ten nodular HCCs in 10 patients were prospectively examined using a 2-4-MHz convex transducer and a standardized examination protocol. Serial US images were obtained before and 20, 30, 40, 50, 60, 90, 120, 150, 180, 240, and 300 s after intravenous injection of 2 g of contrast agent using conventional and harmonic PD US. The percentage of area with Doppler signal within each HCC nodule (%PDA) was calculated in each image with a PC-based image analysis program, and the results with both US techniques were compared.

RESULTS

In the majority of cases, %PDA was greater on conventional PD US than on harmonic PD US. Mean %PDA of 10 HCCs was significantly higher on conventional PD US than on harmonic PD US except at 20 s after injection. The highest values of mean %PDA were 34.9% in conventional PD US and 19.5% in harmonic PD US at 60 s after injection.

CONCLUSION

Area with PD signals within the HCC is smaller and the duration of effective enhancement is shorter in harmonic PD US than in conventional PD US.

摘要

背景

本研究旨在对传统功率多普勒（PD）超声与谐波功率多普勒超声在描绘肝细胞癌（HCC）血管分布方面进行定量比较。

方法

前瞻性地使用2 - 4MHz凸阵探头和标准化检查方案对10例患者的10个结节性HCC进行检查。在静脉注射2g造影剂之前以及注射后20、30、40、50、60、90、120、150、180、240和300秒，分别使用传统和谐波PD超声获取系列超声图像。使用基于计算机的图像分析程序计算每个HCC结节内多普勒信号区域的百分比（%PDA），并比较两种超声技术的结果。