Rosenberg S D, Goodman L A, Osher F C, Swartz M S, Essock S M, Butterfield M I, Constantine N T, Wolford G L, Salyers M P
Department of Psychiatry, Dartmouth Medical School, New Hampshire-Dartmouth Psychiatric Research Center, Lebanon, NH, USA.
Am J Public Health. 2001 Jan;91(1):31-7. doi: 10.2105/ajph.91.1.31.
This study assessed seroprevalence rates of HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) among individuals with severe mental illness.
Participants (n = 931) were patients undergoing inpatient or outpatient treatment in Connecticut, Maryland, New Hampshire, or North Carolina.
The prevalence of HIV infection in this sample (3.1%) was approximately 8 times the estimated US population rate but lower than rates reported in previous studies of people with severe mental illness. Prevalence rates of HBV (23.4%) and HCV (19.6%) were approximately 5 and 11 times the overall estimated population rates for these infections, respectively.
Elevated rates of HIV, HBV, and HCV were found. Of particular concern are the high rates of HCV infection, which are frequently undetected. Individuals with HCV infection commonly fail to receive appropriate treatment to limit liver damage and unknowingly may be a source of infection to others.
本研究评估了患有严重精神疾病的个体中艾滋病毒、乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)的血清流行率。
参与者(n = 931)为在康涅狄格州、马里兰州、新罕布什尔州或北卡罗来纳州接受住院或门诊治疗的患者。
该样本中艾滋病毒感染率(3.1%)约为美国估计人口感染率的8倍,但低于先前对患有严重精神疾病的人群的研究报告的感染率。HBV(23.4%)和HCV(19.6%)的感染率分别约为这些感染总体估计人口感染率的5倍和11倍。
发现艾滋病毒、HBV和HCV的感染率升高。特别令人担忧的是HCV的高感染率,其经常未被检测到。HCV感染者通常未能接受适当治疗以限制肝脏损伤,并且可能在不知不觉中成为他人的传染源。