Miles T P, Palmer R F, Espino D V, Mouton C P, Lichtenstein M J, Markides K S
Department of Family and Community Medicine, University of Texas Health Science Center at San Antonio, USA.
J Gerontol A Biol Sci Med Sci. 2001 Jan;56(1):M19-24. doi: 10.1093/gerona/56.1.m19.
Urinary incontinence in older adults has many distinct etiologies and is associated with lower self-reported health. However, it is unclear whether the new onset of urinary incontinence marks newly emergent frailty.
Using a longitudinal population-based survey of older Mexican Americans (N = 2660) across five south-western states, this study compared the strength of association between markers of physical frailty such as activities of daily living (ADLs), instrumental activities of daily living (IADLs), and performance (timed walk, timed chair rise, and tandem balance) with baseline incontinence (prevalent disease) and new-onset incontinence (incident disease).
We found that 14.1% of the participants (n = 329) were incontinent at baseline (prevalent cases) and 11.6% (n = 208) were newly incontinent 2 years later (incident cases). Controlling for other covariates, prevalent incontinence was only associated with a 60% increased risk of having difficulty walking 8 ft. Incident incontinence was associated with a twofold increased risk of impairment in ADLs and IADLs, and poor performance on all three physical measures.
Incident incontinence is associated with an increased risk of more global functional impairment. Thus, incident disease may be an important early marker for signaling the onset of frailty among persons who become incontinent after the age of 65 years.
老年人尿失禁有多种不同病因,且与自我报告的健康状况较差相关。然而,尚不清楚尿失禁的新发是否标志着新出现的衰弱。
本研究对美国西南部五个州的墨西哥裔美国老年人(N = 2660)进行了一项基于人群的纵向调查,比较了身体衰弱标志物(如日常生活活动能力(ADL)、工具性日常生活活动能力(IADL)和表现(定时步行、定时从椅子上起身和串联平衡))与基线尿失禁(患病)和新发尿失禁(发病)之间的关联强度。
我们发现,14.1%的参与者(n = 329)在基线时存在尿失禁(患病病例),11.6%(n = 208)在两年后新发尿失禁(发病病例)。在控制其他协变量后,患病尿失禁仅与行走8英尺困难风险增加60%相关。发病尿失禁与ADL和IADL受损风险增加两倍以及所有三项身体测量表现不佳相关。
发病尿失禁与更广泛的功能损害风险增加相关。因此,发病疾病可能是65岁后出现尿失禁的人群中衰弱开始的一个重要早期标志。