Ottenbacher Kenneth J, Ostir Glenn V, Peek M Kristen, Snih Soham Al, Raji Mukaila A, Markides Kyriakos S
Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, Texas 77555, USA.
J Am Geriatr Soc. 2005 Sep;53(9):1524-31. doi: 10.1111/j.1532-5415.2005.53511.x.
To identify sociodemographic characteristics and health performance variables associated with frailty in older Mexican Americans.
A prospective population-based survey.
Homes of older adults living in the southwest.
Six hundred twenty-one noninstitutionalized Mexican-American men and women aged 70 and older included in the Hispanic Established Populations for Epidemiologic Study of the Elderly participated in a home-based interview.
Interviews included information on sociodemographics, self-reports of medical conditions (arthritis, diabetes mellitus, heart attack, hip fracture, cancer, and stroke) and functional status. Weight and measures of lower and upper extremity muscle strength were obtained along with information on activities of daily living and instrumental activities of daily living. A summary measure of frailty was created based on weight loss, exhaustion, grip strength, and walking speed. Multivariable linear regression identified variables associated with frailty at baseline. Logistic regression examined variables predicting frailty at 1-year follow-up.
Sex was associated with frailty at baseline (F=4.28, P=.03). Predictors of frailty in men included upper extremity strength, disability (activities of daily living), comorbidities, and mental status scores (Nagelkerke coefficient of determination (R(2))=0.37). Predictors for women included lower extremity strength, disability (activities of daily living), and body mass index (Nagelkerke R(2)=0.29). At 1-year follow-up, 83% of men and 79% of women were correctly classified as frail.
Different variables were identified as statistically significant predictors of frailty in Mexican-American men and women aged 70 and older. The prevention, development, and treatment of frailty in older Mexican Americans may require consideration of the unique characteristics of this population.
确定与墨西哥裔美国老年人虚弱相关的社会人口学特征和健康表现变量。
一项基于人群的前瞻性调查。
居住在西南部的老年人的家中。
纳入西班牙裔老年人流行病学研究既定人群的621名70岁及以上的非机构化墨西哥裔美国男性和女性参与了一次居家访谈。
访谈内容包括社会人口学信息、医疗状况(关节炎、糖尿病、心脏病发作、髋部骨折、癌症和中风)的自我报告以及功能状态。获取了体重、下肢和上肢肌肉力量的测量数据以及日常生活活动和工具性日常生活活动的信息。基于体重减轻、疲惫、握力和步行速度创建了一个虚弱的综合测量指标。多变量线性回归确定了基线时与虚弱相关的变量。逻辑回归检验了预测1年随访时虚弱的变量。
性别与基线时的虚弱相关(F = 4.28,P = 0.03)。男性虚弱的预测因素包括上肢力量、残疾(日常生活活动)、合并症和精神状态评分(Nagelkerke决定系数(R²)= 0.37)。女性的预测因素包括下肢力量、残疾(日常生活活动)和体重指数(Nagelkerke R² = 0.29)。在1年随访时,83%的男性和79%的女性被正确分类为虚弱。
在70岁及以上的墨西哥裔美国男性和女性中,不同的变量被确定为虚弱的统计学显著预测因素。墨西哥裔美国老年人虚弱的预防、发展和治疗可能需要考虑该人群的独特特征。