Cassel C K
Henry L. Schwartz Department of Geriatrics and Adult Development, Mount Sinai School of Medicine, New York, NY, USA.
Geriatrics. 2001 Jan;56(1):35-9; quiz 40.
If the unprecedented increase in life expectancy has a downside, it is the exposure of risk to chronic age-related disorders. As clinicians work to foster healthy aging, we must also seek ways to prevent the disabling disorders that keep many older persons from enjoying their longevity. The high prevalence of chronic illness and functional limitation among older persons underscores the need for strategically directed health and social services. Successful patient management must extend beyond diagnosis and disease treatment and include promotion of function and prevention of decline. Achieving this goal requires a seamless continuum of management and interdisciplinary caregiving. There also must be a focus on improving the understanding of the science of aging. New treatment approaches for managing aging may one day include cognitive enhancers, designer hormones, telomerase, antioxidants, and gene therapy.
如果预期寿命的空前增长存在不利之处,那就是面临与年龄相关的慢性疾病风险。当临床医生致力于促进健康老龄化时,我们还必须寻求方法来预防那些使许多老年人无法享受长寿的致残性疾病。老年人中慢性病和功能受限的高患病率凸显了对有战略导向的健康和社会服务的需求。成功的患者管理必须超越诊断和疾病治疗,还应包括促进功能和预防衰退。实现这一目标需要无缝的连续管理和跨学科护理。还必须注重增进对衰老科学的理解。未来某一天,管理衰老的新治疗方法可能包括认知增强剂、定制激素、端粒酶、抗氧化剂和基因疗法。