Ferrand E, Robert R, Ingrand P, Lemaire F
Surgical Unit, Henri-Mondor University Hospital, Créteil, France.
Lancet. 2001 Jan 6;357(9249):9-14. doi: 10.1016/s0140-6736(00)03564-9.
In France, there are no guidelines available on withholding and withdrawal of life-sustaining treatments, and information on the frequency of such decisions is scarce.
We undertook a prospective 2-month survey in 113, of a total of 220, intensive-care units (ICUs) in France to study the frequency of, and processes leading to, decisions to withhold and withdraw life-sustaining treatments.
Life-supporting therapies were withheld or withdrawn in 807 (11.0%) of 7309 patients (withholding in 336 [4.6%] and withdrawal in 471 [6.4%], preceded in 358 by withholding). Of 1175 deaths in ICU, 628 (53%) were preceded by a decision to limit life-supporting therapies. Futility and poor expected quality of life were the most frequently cited reasons. Decisions were strongly correlated with the simplified acute physiological score, but an independent centre effect persisted after adjustment for this score. Decisions were mostly taken by all the ICU medical staff, with (54%) or without (34%) the nursing staff; however, a single physician made decisions in 12% of cases. The patient's family was involved in the decision-making process in 44% of cases. The patient's willingness to limit his or her own care was known in only 8% of the cases; only 0.5% of the patients were involved in decisions.
Withholding and withdrawal of life-support therapies are widely practised in French ICUs, despite their prohibition by the French legislation. The lack of an official statement from French scientific bodies may explain several limitations on the various steps of the decision-making process.
在法国,关于停止和撤销维持生命治疗尚无可用指南,且此类决策的频率信息匮乏。
我们在法国220个重症监护病房(ICU)中的113个进行了为期2个月的前瞻性调查,以研究停止和撤销维持生命治疗的决策频率及相关流程。
在7309例患者中,有807例(11.0%)接受了停止或撤销生命支持治疗(336例[4.6%]为停止,471例[6.4%]为撤销,其中358例在撤销前已停止)。在ICU的1175例死亡病例中,628例(53%)之前有过限制生命支持治疗的决策。最常提及的原因是治疗无意义和预期生活质量差。决策与简化急性生理学评分密切相关,但在对该评分进行调整后,独立的中心效应仍然存在。决策大多由ICU全体医务人员做出,有(54%)或没有(34%)护理人员参与;然而,12%的病例由单一医生做出决策。44%的病例中患者家属参与了决策过程。仅8%的病例了解患者限制自身治疗的意愿;仅0.5%的患者参与了决策。
尽管法国法律禁止,但在法国ICU中广泛存在停止和撤销生命支持治疗的情况。法国科学机构缺乏官方声明可能解释了决策过程各个环节存在的若干局限性。