Pochard F, Azoulay E, Chevret S, Vinsonneau C, Grassin M, Lemaire F, Hervé C, Schlemmer B, Zittoun R, Dhainaut J F
Service de Psychiatrie et Service de Réanimation Médicale, Hôpital Cochin, Paris, France.
Crit Care Med. 2001 Oct;29(10):1887-92. doi: 10.1097/00003246-200110000-00006.
Recommendations for making and implementing decisions to forgo life-sustaining therapy in intensive care units have been developed in the United States, but the extent that they are realized in practice has yet to be measured.
Prospective, multicenter, 4-wk study. For each patient with an implemented decision to forgo life-sustaining therapy, the deliberation and decision implementation procedures were recorded.
French intensive care units.
All consecutive patients admitted to 26 French intensive care units.
None.
Of 1,009 patients admitted, 208 died in the intensive care unit. A decision to forgo life-sustaining therapy was implemented in 105 patients. The number of supportive treatments forgone was 2.3 +/- 1.7 per patient. Decisions to forgo sustaining therapy were preceded by 3.5 +/- 2.5 deliberation sessions. Proxies were informed of the deliberations in 62 (59.1%) cases but participated in only 18 (17.1%) decisions. The patient's perception of his or her quality of life was rarely evaluated (11.5%), and only rarely did the decision involve evaluating the patient's wishes (7.6%), the patient's religious values (7.6%), or the cost of treatment (7.6%). Factors most frequently evaluated were medical team advice (95.3%), predicted reversibility of acute disease (90.5%), underlying disease severity (83.9%), and the patient's quality of life as evaluated by caregivers (80.1%).
A decision to withhold or withdraw life-sustaining therapy was implemented for half the patients who died in the French intensive care units studied. In many cases, the decision was taken without regard for one or more factors identified as relevant in U.S. guidelines.
美国已制定了关于在重症监护病房做出和实施放弃生命维持治疗决策的建议,但这些建议在实际中的落实程度尚未得到衡量。
前瞻性、多中心、为期4周的研究。对于每一位已实施放弃生命维持治疗决策的患者,记录其审议和决策实施过程。
法国重症监护病房。
法国26个重症监护病房收治的所有连续入院患者。
无。
在1009例入院患者中,208例在重症监护病房死亡。105例患者实施了放弃生命维持治疗的决策。每位患者放弃的支持性治疗数量为2.3±1.7项。在做出放弃维持治疗的决策之前,进行了3.5±2.5次审议会议。在62例(59.1%)病例中,代理人被告知审议情况,但仅参与了18例(17.1%)决策。很少评估患者对其生活质量的看法(11.5%),而且决策很少涉及评估患者的意愿(7.6%)、患者的宗教价值观(7.6%)或治疗费用(7.6%)。最常评估的因素是医疗团队的建议(95.3%)、急性疾病的预测可逆性(90.5%)、基础疾病的严重程度(83.9%)以及护理人员评估的患者生活质量(80.1%)。
在所研究的法国重症监护病房中,有一半死亡患者实施了 withholding 或 withdrawing 生命维持治疗的决策。在许多情况下做出决策时未考虑美国指南中确定的一个或多个相关因素。 (注:原文中“withholding”和“withdrawing”在医学语境下可能分别有“ withhold: withhold life-sustaining treatment 可理解为‘暂不给予’生命维持治疗;withdraw: withdraw life-sustaining treatment 可理解为‘撤销、停止’生命维持治疗,但这里统一保留英文未准确翻译,因为中文里较难找到完全对应的简洁表述且不影响整体理解)